Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4279162..4279307 Replicon chromosome
Accession NZ_OV049808
Organism Klebsiella pneumoniae strain DJ isolate DJ

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4279198..4279300 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4279162..4279307 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LRA90_RS20785 4274292..4276352 + 2061 WP_004151449.1 oligopeptidase B -
LRA90_RS20790 4276356..4277015 - 660 WP_002911407.1 exodeoxyribonuclease X -
LRA90_RS20795 4277094..4277324 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LRA90_RS20800 4277437..4277811 + 375 WP_039819395.1 CopC domain-containing protein YobA -
LRA90_RS20805 4277815..4278684 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
LRA90_RS20810 4278701..4279039 + 339 WP_002911404.1 YebY family protein -
- 4279162..4279307 - 146 - - Antitoxin
- 4279198..4279300 + 103 - - Toxin
LRA90_RS20815 4279676..4279819 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
LRA90_RS20820 4279924..4280892 - 969 WP_014907334.1 VirK/YbjX family protein -
LRA90_RS20825 4281049..4281702 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
LRA90_RS20830 4281699..4281890 - 192 WP_002911395.1 YebW family protein -
LRA90_RS20835 4281988..4282227 - 240 WP_002911393.1 YebV family protein -
LRA90_RS20840 4282343..4283776 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T294986 NZ_OV049808:4279198-4279300 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT294986 NZ_OV049808:c4279307-4279162 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References