Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 3682475..3683095 Replicon chromosome
Accession NZ_OU963893
Organism Unidentified bacterial endosymbiont isolate Enterobacter_chilo

Toxin (Protein)


Gene name Hha Uniprot ID -
Locus tag NL510_RS17670 Protein ID WP_253378797.1
Coordinates 3682877..3683095 (+) Length 73 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID -
Locus tag NL510_RS17665 Protein ID WP_253378795.1
Coordinates 3682475..3682849 (+) Length 125 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL510_RS17655 3677599..3678792 + 1194 WP_253378793.1 multidrug efflux RND transporter periplasmic adaptor subunit AcrA -
NL510_RS17660 3678815..3681962 + 3148 Protein_3451 multidrug efflux RND transporter permease subunit AcrB -
NL510_RS17665 3682475..3682849 + 375 WP_253378795.1 Hha toxicity modulator TomB Antitoxin
NL510_RS17670 3682877..3683095 + 219 WP_253378797.1 HHA domain-containing protein Toxin
NL510_RS17675 3683303..3683854 + 552 WP_253378799.1 maltose O-acetyltransferase -
NL510_RS17680 3683972..3684439 + 468 WP_253378801.1 YlaC family protein -
NL510_RS17685 3684483..3684623 - 141 WP_253378803.1 type B 50S ribosomal protein L36 -
NL510_RS17690 3684626..3684886 - 261 WP_253378805.1 type B 50S ribosomal protein L31 -
NL510_RS17695 3685120..3686688 + 1569 WP_253378808.1 EAL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(13-69)

Antitoxin

Biofilm formation regulator YbaJ

(1-115)


Sequences

Toxin        


Download         Length: 73 a.a.        Molecular weight: 8607.99 Da        Isoelectric Point: 8.9008

>T294958 WP_253378797.1 NZ_OU963893:3682877-3683095 [unidentified bacterial endosymbiont]
MTEKPLTKIDYLLRLRRCQSLDTLERVIEKNKYELSDNELAVFYSAADHRLAELTMNKLYDKIPSSVWKFVR

Download         Length: 219 bp

Antitoxin


Download         Length: 125 a.a.        Molecular weight: 14481.28 Da        Isoelectric Point: 4.8886

>AT294958 WP_253378795.1 NZ_OU963893:3682475-3682849 [unidentified bacterial endosymbiont]
MDEYSPKRHDIAQLKFLCESLYHDCLANLDESNHGWVNDPTSAINLQLNELIEHIATFALNYKIKYNEDNKLIEQIDEYL
DDTFMLFSSYGINVQDLQKWRKSGNRLFRCFVNASRANPVSLSC

Download         Length: 375 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References