Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1064294..1064951 Replicon chromosome
Accession NZ_OU963893
Organism Unidentified bacterial endosymbiont isolate Enterobacter_chilo

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag NL510_RS05080 Protein ID WP_253382143.1
Coordinates 1064541..1064951 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag NL510_RS05075 Protein ID WP_253382141.1
Coordinates 1064294..1064560 (+) Length 89 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL510_RS05050 1059529..1059711 + 183 Protein_979 NAD(P)-dependent oxidoreductase -
NL510_RS05055 1059767..1061200 - 1434 WP_253382135.1 6-phospho-beta-glucosidase -
NL510_RS05060 1061317..1062048 - 732 WP_253384755.1 MurR/RpiR family transcriptional regulator -
NL510_RS05065 1062314..1062973 + 660 WP_253382137.1 hemolysin III family protein -
NL510_RS05070 1063019..1063999 - 981 WP_253382139.1 tRNA-modifying protein YgfZ -
NL510_RS05075 1064294..1064560 + 267 WP_253382141.1 FAD assembly factor SdhE Antitoxin
NL510_RS05080 1064541..1064951 + 411 WP_253382143.1 protein YgfX Toxin
NL510_RS05085 1064957..1065478 - 522 WP_253382146.1 flavodoxin FldB -
NL510_RS05090 1065580..1066476 + 897 WP_253384758.1 site-specific tyrosine recombinase XerD -
NL510_RS05095 1066505..1067218 + 714 WP_253382148.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NL510_RS05100 1067224..1068957 + 1734 WP_253382150.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-132)

Antitoxin

(7-79)


Sequences


Toxin        


Download         Length: 137 a.a.        Molecular weight: 16148.01 Da        Isoelectric Point: 11.8921

>T294951 WP_253382143.1 NZ_OU963893:1064541-1064951 [unidentified bacterial endosymbiont]
VVLWQSDLRVSWRSQWMSLMLHGVVAALVLLMPWPLSYTPVWLLMLSFVVFDSVRSQRRINARQGEIKLLVDSRLRWQGK
EWEIVGMPWMLRSGMMLRLRNAGGGRRQHLWLASDSMDIAEWRDLRRTFLQQPTQE

Download         Length: 411 bp


Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10528.99 Da        Isoelectric Point: 5.6254

>AT294951 WP_253382141.1 NZ_OU963893:1064294-1064560 [unidentified bacterial endosymbiont]
MDINNKARLHWACRRGMRELDISIMPFFEHEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References