Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1974613..1974756 Replicon chromosome
Accession NZ_OU943336
Organism Salmonella enterica subsp. enterica serovar Typhi strain MDUST305

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1974652..1974754 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1974613..1974756 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AEG13_RS09575 (SAMEA1964467_01930) 1971037..1971735 - 699 WP_000944282.1 exodeoxyribonuclease X -
AEG13_RS09580 (SAMEA1964467_01931) 1971759..1972415 - 657 WP_000100250.1 carbon-nitrogen hydrolase family protein -
AEG13_RS09585 (SAMEA1964467_01932) 1972523..1972753 - 231 WP_000856224.1 DNA polymerase III subunit theta -
AEG13_RS09590 (SAMEA1964467_01933) 1972891..1973265 + 375 WP_001681742.1 CopC domain-containing protein YobA -
AEG13_RS09595 (SAMEA1964467_01934) 1973266..1974141 + 876 WP_000979693.1 copper homeostasis membrane protein CopD -
AEG13_RS09600 (SAMEA1964467_01935) 1974158..1974511 + 354 WP_000722366.1 YebY family protein -
- 1974613..1974756 - 144 - - Antitoxin
- 1974652..1974754 + 103 - - Toxin
AEG13_RS09605 (SAMEA1964467_01936) 1974875..1975183 - 309 Protein_1877 tyrosine-type recombinase/integrase -
AEG13_RS09610 1975182..1975543 - 362 Protein_1878 recombinase RecT -
AEG13_RS09615 1975544..1975654 + 111 Protein_1879 replication protein -
AEG13_RS09620 1975667..1976062 + 396 Protein_1880 DUF977 family protein -
AEG13_RS09625 (SAMEA1964467_01938) 1976348..1977478 - 1131 WP_000529513.1 GGDEF domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 1952740..2005943 53203


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T294909 NZ_OU943336:1974652-1974754 [Salmonella enterica subsp. enterica serovar Typhi]
GCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 144 bp

>AT294909 NZ_OU943336:c1974756-1974613 [Salmonella enterica subsp. enterica serovar Typhi]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCTCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References