Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 2114120..2114630 Replicon chromosome
Accession NZ_OU912926
Organism Candidatus Nitrotoga arctica strain 6680 isolate 6680

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag MKZ32_RS09660 Protein ID WP_239797078.1
Coordinates 2114364..2114630 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag MKZ32_RS09655 Protein ID WP_239797077.1
Coordinates 2114120..2114380 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MKZ32_RS09635 (NTG6680_2011) 2109736..2109900 - 165 WP_239797073.1 hypothetical protein -
MKZ32_RS09640 (NTG6680_2012) 2110069..2112825 + 2757 WP_239797074.1 lactate dehydrogenase -
MKZ32_RS09645 (NTG6680_2013) 2112822..2113895 + 1074 WP_239797075.1 hypothetical protein -
MKZ32_RS09650 (NTG6680_2014) 2113892..2114065 + 174 WP_239797076.1 hypothetical protein -
MKZ32_RS09655 (NTG6680_2015) 2114120..2114380 + 261 WP_239797077.1 DUF6290 family protein Antitoxin
MKZ32_RS09660 (NTG6680_2016) 2114364..2114630 + 267 WP_239797078.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MKZ32_RS09665 (NTG6680_2017) 2114639..2114827 + 189 WP_239797079.1 hypothetical protein -
MKZ32_RS09670 (NTG6680_2018) 2115274..2116074 + 801 WP_239797080.1 DEAD/DEAH box helicase family protein -
MKZ32_RS09675 (NTG6680_2019) 2116071..2117399 + 1329 WP_239797081.1 hypothetical protein -
MKZ32_RS09680 (NTG6680_2020) 2117392..2118573 + 1182 WP_239797082.1 GIY-YIG nuclease family protein -
MKZ32_RS09685 (NTG6680_2021) 2118712..2119293 - 582 WP_239797083.1 redoxin domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-87)

Antitoxin

Protein of unknown function DUF6290

(12-82)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10229.76 Da        Isoelectric Point: 10.3399

>T294902 WP_239797078.1 NZ_OU912926:2114364-2114630 [Candidatus Nitrotoga arctica]
MAWTIDYAETAKAQLRKLDKQTARRIVDFMDERVAGRENPRDSGKALTGSLGGFWRYRVRDCRVICDIQDGVLRVLVVQV
GNRREIYR

Download         Length: 267 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9945.18 Da        Isoelectric Point: 4.8728

>AT294902 WP_239797077.1 NZ_OU912926:2114120-2114380 [Candidatus Nitrotoga arctica]
VNTRIQLETLNMATSIRLAPEIEQRLDYLASHTGRTKAYYLREIIEHGIEEMEDYYLAADVLERVRKGQEQVHSAADVRK
DLGLDN

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References