Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 1815999..1816669 Replicon chromosome
Accession NZ_OU912926
Organism Candidatus Nitrotoga arctica strain 6680 isolate 6680

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag MKZ32_RS08190 Protein ID WP_239796830.1
Coordinates 1816247..1816669 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag MKZ32_RS08185 Protein ID WP_239796829.1
Coordinates 1815999..1816250 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MKZ32_RS08160 (NTG6680_1710) 1811017..1813167 - 2151 WP_239796824.1 bifunctional TVP38/TMEM64 family protein/FAD-dependent oxidoreductase -
MKZ32_RS08165 (NTG6680_1711) 1813164..1814141 - 978 WP_239796825.1 arsenosugar biosynthesis radical SAM protein ArsS -
MKZ32_RS08170 (NTG6680_1712) 1814348..1814758 - 411 WP_239796826.1 hypothetical protein -
MKZ32_RS08175 (NTG6680_1714) 1815051..1815368 - 318 WP_239796827.1 type II toxin-antitoxin system RelE/ParE family toxin -
MKZ32_RS08180 (NTG6680_1715) 1815368..1815667 - 300 WP_239796828.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
MKZ32_RS08185 (NTG6680_1716) 1815999..1816250 + 252 WP_239796829.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
MKZ32_RS08190 (NTG6680_1717) 1816247..1816669 + 423 WP_239796830.1 PIN domain-containing protein Toxin
MKZ32_RS08195 (NTG6680_1718) 1816744..1816896 - 153 WP_239796831.1 hypothetical protein -
MKZ32_RS08200 (NTG6680_1719) 1816923..1817333 - 411 WP_239796832.1 hypothetical protein -
MKZ32_RS08205 (NTG6680_1720) 1817345..1818652 - 1308 WP_239796833.1 hypothetical protein -
MKZ32_RS08210 (NTG6680_1721) 1818780..1819868 - 1089 WP_239796834.1 lipocalin family protein -
MKZ32_RS08215 (NTG6680_1722) 1819871..1820806 - 936 WP_239796835.1 diguanylate cyclase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-122)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-71)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15680.25 Da        Isoelectric Point: 6.8604

>T294900 WP_239796830.1 NZ_OU912926:1816247-1816669 [Candidatus Nitrotoga arctica]
MSWLLDTCALSEYAKKAPTPKVIAWLDEQDETSLFISVITLGEIEKGILKLRANDPHRSQKLTAWLGKVEQRFAGRILPL
NAAALHVWAQITAHSELTGQPMPVMDGLLMATAQCHGFTVVTRYVQDFAMYPQVFNPWAL

Download         Length: 423 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9238.46 Da        Isoelectric Point: 8.6984

>AT294900 WP_239796829.1 NZ_OU912926:1815999-1816250 [Candidatus Nitrotoga arctica]
MHREWQLQKAKGNFSQLIKEAVSGDAQVVTVHGKPTAVIVSAEEYARLTRHRTKLSSALLRPDLAAEDLDISRSRDAGRD
IDL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References