Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/VapC-Phd |
Location | 1815999..1816669 | Replicon | chromosome |
Accession | NZ_OU912926 | ||
Organism | Candidatus Nitrotoga arctica strain 6680 isolate 6680 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | MKZ32_RS08190 | Protein ID | WP_239796830.1 |
Coordinates | 1816247..1816669 (+) | Length | 141 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | - |
Locus tag | MKZ32_RS08185 | Protein ID | WP_239796829.1 |
Coordinates | 1815999..1816250 (+) | Length | 84 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
MKZ32_RS08160 (NTG6680_1710) | 1811017..1813167 | - | 2151 | WP_239796824.1 | bifunctional TVP38/TMEM64 family protein/FAD-dependent oxidoreductase | - |
MKZ32_RS08165 (NTG6680_1711) | 1813164..1814141 | - | 978 | WP_239796825.1 | arsenosugar biosynthesis radical SAM protein ArsS | - |
MKZ32_RS08170 (NTG6680_1712) | 1814348..1814758 | - | 411 | WP_239796826.1 | hypothetical protein | - |
MKZ32_RS08175 (NTG6680_1714) | 1815051..1815368 | - | 318 | WP_239796827.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
MKZ32_RS08180 (NTG6680_1715) | 1815368..1815667 | - | 300 | WP_239796828.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | - |
MKZ32_RS08185 (NTG6680_1716) | 1815999..1816250 | + | 252 | WP_239796829.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
MKZ32_RS08190 (NTG6680_1717) | 1816247..1816669 | + | 423 | WP_239796830.1 | PIN domain-containing protein | Toxin |
MKZ32_RS08195 (NTG6680_1718) | 1816744..1816896 | - | 153 | WP_239796831.1 | hypothetical protein | - |
MKZ32_RS08200 (NTG6680_1719) | 1816923..1817333 | - | 411 | WP_239796832.1 | hypothetical protein | - |
MKZ32_RS08205 (NTG6680_1720) | 1817345..1818652 | - | 1308 | WP_239796833.1 | hypothetical protein | - |
MKZ32_RS08210 (NTG6680_1721) | 1818780..1819868 | - | 1089 | WP_239796834.1 | lipocalin family protein | - |
MKZ32_RS08215 (NTG6680_1722) | 1819871..1820806 | - | 936 | WP_239796835.1 | diguanylate cyclase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 141 a.a. Molecular weight: 15680.25 Da Isoelectric Point: 6.8604
>T294900 WP_239796830.1 NZ_OU912926:1816247-1816669 [Candidatus Nitrotoga arctica]
MSWLLDTCALSEYAKKAPTPKVIAWLDEQDETSLFISVITLGEIEKGILKLRANDPHRSQKLTAWLGKVEQRFAGRILPL
NAAALHVWAQITAHSELTGQPMPVMDGLLMATAQCHGFTVVTRYVQDFAMYPQVFNPWAL
MSWLLDTCALSEYAKKAPTPKVIAWLDEQDETSLFISVITLGEIEKGILKLRANDPHRSQKLTAWLGKVEQRFAGRILPL
NAAALHVWAQITAHSELTGQPMPVMDGLLMATAQCHGFTVVTRYVQDFAMYPQVFNPWAL
Download Length: 423 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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