Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-YefM
Location 568071..568573 Replicon chromosome
Accession NZ_OU912926
Organism Candidatus Nitrotoga arctica strain 6680 isolate 6680

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag MKZ32_RS02680 Protein ID WP_239795851.1
Coordinates 568071..568325 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MKZ32_RS02685 Protein ID WP_239795852.1
Coordinates 568322..568573 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MKZ32_RS02660 (NTG6680_0547) 564649..565896 - 1248 WP_239795848.1 diaminopimelate decarboxylase -
MKZ32_RS02665 565899..566003 - 105 WP_239798080.1 lipoprotein -
MKZ32_RS02670 (NTG6680_0548) 566179..566721 - 543 WP_239795849.1 transposase -
MKZ32_RS02675 (NTG6680_0549) 566819..567718 - 900 WP_239795850.1 HEPN domain-containing protein -
MKZ32_RS02680 (NTG6680_0550) 568071..568325 - 255 WP_239795851.1 Txe/YoeB family addiction module toxin Toxin
MKZ32_RS02685 (NTG6680_0551) 568322..568573 - 252 WP_239795852.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
MKZ32_RS02690 (NTG6680_0552) 568804..569241 - 438 WP_239795853.1 DUF3592 domain-containing protein -
MKZ32_RS02695 (NTG6680_0553) 569386..569733 - 348 WP_239795854.1 DNA-binding protein -
MKZ32_RS02700 569714..570046 - 333 WP_239795855.1 DUF6516 family protein -
MKZ32_RS02705 (NTG6680_0554) 570105..570848 - 744 WP_239795856.1 SprT family zinc-dependent metalloprotease -
MKZ32_RS02710 (NTG6680_0555) 570848..571552 - 705 WP_239795857.1 lysophospholipid acyltransferase family protein -
MKZ32_RS02715 (NTG6680_0556) 571627..572157 - 531 WP_239795858.1 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10228.77 Da        Isoelectric Point: 8.0472

>T294898 WP_239795851.1 NZ_OU912926:c568325-568071 [Candidatus Nitrotoga arctica]
VRLIFADDAWEDYLYWQKQDKRMVERINKLIRETQREPFAGIGKPEQLKHALSGFWSRRITDEHRMVYCIEGDALMIAQL
RFHY

Download         Length: 255 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9248.66 Da        Isoelectric Point: 8.0000

>AT294898 WP_239795852.1 NZ_OU912926:c568573-568322 [Candidatus Nitrotoga arctica]
MNAITYTTVRANLASAMDRVCDDHEPLIITRNGEQSVVMLSLEDYKSLEETAYLLRTPANAKRLLTAIAQLNNGKGVERK
LVK

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References