Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 948043..948695 Replicon chromosome
Accession NZ_OU907312
Organism Unidentified bacterial endosymbiont isolate unidentified_bacterial_endosymbiont_Chironomus_riparius

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NL324_RS04765 Protein ID WP_253306546.1
Coordinates 948273..948695 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NL324_RS04760 Protein ID WP_253306545.1
Coordinates 948043..948273 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL324_RS04745 943676..944986 - 1311 WP_253306542.1 anti-phage deoxyguanosine triphosphatase -
NL324_RS04750 944973..945569 - 597 WP_253306543.1 5'-deoxynucleotidase -
NL324_RS04755 945622..947670 - 2049 WP_253306544.1 methionine--tRNA ligase -
NL324_RS04760 948043..948273 + 231 WP_253306545.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
NL324_RS04765 948273..948695 + 423 WP_253306546.1 tRNA(fMet)-specific endonuclease VapC Toxin
NL324_RS04770 948780..948986 - 207 Protein_914 helix-turn-helix domain-containing protein -
NL324_RS04775 949051..949242 + 192 Protein_915 chorismate-binding protein -
NL324_RS04780 949343..949531 + 189 WP_253306547.1 hypothetical protein -
NL324_RS04785 949566..950084 + 519 WP_253305868.1 helix-turn-helix domain-containing protein -
NL324_RS04790 950081..950575 + 495 WP_253305867.1 IS630 family transposase -
NL324_RS04795 950585..951844 + 1260 WP_253306548.1 FAD-binding oxidoreductase -
NL324_RS04805 952541..952957 - 417 WP_253306549.1 CesT family type III secretion system chaperone -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-56)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15641.94 Da        Isoelectric Point: 7.7971

>T294892 WP_253306546.1 NZ_OU907312:948273-948695 [unidentified bacterial endosymbiont]
MLQYLLDTNICIFTIKNKPREVCDTFKYHHGQICISSITLMELIYGAEKSANKKKNLDIIEGFSARLEVLTYDASAAQHS
GQLRAELARNGKSIGPYDQMIAGHARSKGLIIVTNNLREFERVPGLRSVDWTPSGDGPME

Download         Length: 423 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8675.80 Da        Isoelectric Point: 4.5258

>AT294892 WP_253306545.1 NZ_OU907312:948043-948273 [unidentified bacterial endosymbiont]
MEQTTIFKSNRSQAVRLPKAVALPDDVKRVDIVAIGRTRIITPAGEIWDTWFDGPPADNDFMAIREQSTDQIREEF

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References