Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 2877019..2877628 Replicon chromosome
Accession NZ_OU745390
Organism Pseudomonas sp. Marseille-Q3773

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag LG386_RS13330 Protein ID WP_225778761.1
Coordinates 2877019..2877321 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag LG386_RS13335 Protein ID WP_186688533.1
Coordinates 2877314..2877628 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LG386_RS25660 2872874..2873002 - 129 WP_009683677.1 PA1414 family protein -
LG386_RS13310 2873127..2874020 - 894 WP_225778757.1 LysR family transcriptional regulator -
LG386_RS13315 2874126..2875295 + 1170 WP_225778758.1 MFS transporter -
LG386_RS13320 2875423..2876349 - 927 WP_225778759.1 DMT family transporter -
LG386_RS13325 2876456..2876851 - 396 WP_225778760.1 transcriptional regulator -
LG386_RS13330 2877019..2877321 + 303 WP_225778761.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LG386_RS13335 2877314..2877628 + 315 WP_186688533.1 putative addiction module antidote protein Antitoxin
LG386_RS13340 2877680..2877952 + 273 WP_225778762.1 hypothetical protein -
LG386_RS13345 2878124..2879446 - 1323 WP_225778763.1 DEAD/DEAH box helicase -
LG386_RS13350 2879588..2880889 + 1302 WP_225778764.1 mechanosensitive ion channel family protein -
LG386_RS13355 2880934..2881230 - 297 WP_225778765.1 DUF3077 domain-containing protein -
LG386_RS13360 2881327..2881569 - 243 WP_225778766.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2869162..2879446 10284


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(6-94)

Antitoxin

Uncharacterized protein HI1420

(8-97)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11316.93 Da        Isoelectric Point: 10.8773

>T294888 WP_225778761.1 NZ_OU745390:2877019-2877321 [Pseudomonas sp. Marseille-Q3773]
MKKIESSSFRHWVTGLRDANARARIISRINRLMEGLPGDVSPVGHGVSELRVHYGPGYRVYFHQAGNTFVILLCGGDKGS
QQRDIKAAHQILRSWRMQND

Download         Length: 303 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11306.83 Da        Isoelectric Point: 6.2193

>AT294888 WP_186688533.1 NZ_OU745390:2877314-2877628 [Pseudomonas sp. Marseille-Q3773]
MTETFSEFDPAQYLTTPEAIAQFMTDALETGDAGYVAKAVGVVARAKGMSELAKETGLSREQLYRSFSEHGNPTLKSFLT
VMKALGIDMTAQPHLAGHRSRPLN

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References