Detailed information of TA system TA294887

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 983904..984787
• Replicon: chromosome
• Accession: NZ_OU745390
• Organism: Pseudomonas sp. Marseille-Q3773

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: LG386_RS04515
• Protein ID: WP_225777286.1
• Coordinates: 984350..984787 (+)
• Length: 146 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: LG386_RS04510
• Protein ID: WP_225777285.1
• Coordinates: 983904..984353 (+)
• Length: 150 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LG386_RS04485	979331..980530	+	1200	WP_225777281.1	sugar transporter	-
LG386_RS04490	980592..981176	-	585	WP_225777282.1	LysE family translocator	-
LG386_RS04495	981227..982057	-	831	WP_225777283.1	AraC family transcriptional regulator	-
LG386_RS04500	982105..983013	-	909	WP_225777284.1	LysR family transcriptional regulator	-
LG386_RS04505	983118..983771	+	654	WP_200626111.1	oxygen-insensitive NAD(P)H nitroreductase	-
LG386_RS04510	983904..984353	+	450	WP_225777285.1	DUF2384 domain-containing protein	Antitoxin
LG386_RS04515	984350..984787	+	438	WP_225777286.1	RES family NAD+ phosphorylase	Toxin
LG386_RS04520	984794..985948	-	1155	WP_225777287.1	aminotransferase class V-fold PLP-dependent enzyme	-
LG386_RS04525	986146..987072	-	927	WP_225777288.1	LysR family transcriptional regulator	-
LG386_RS04530	987213..988442	+	1230	WP_225777289.1	acyl-CoA dehydrogenase	-
LG386_RS04535	988507..989301	-	795	WP_225777290.1	OBAP family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-138)

Antitoxin

• Antitoxin Xre (28-146)

Sequences

Toxin

Protein

• Length: 146 a.a.
• Molecular weight: 16087.37 Da
• Isoelectric Point: 6.0736

>T294887 WP_225777286.1 NZ_OU745390:984350-984787 [Pseudomonas sp. Marseille-Q3773]
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPAGAMLEVLVHLEIDPEDFPTTMRLLRIELPDTVSQAQLPPLQ
PGWSTQTELTRGLGNRFLDDCSALLLPVPSAIMPRTTNYLFNPRHPQAHSARLEVEDFTPDSRLF

Nucleotide

• Length: 438 bp

Antitoxin

Protein

• Length: 150 a.a.
• Molecular weight: 16974.56 Da
• Isoelectric Point: 6.3398

>AT294887 WP_225777285.1 NZ_OU745390:983904-984353 [Pseudomonas sp. Marseille-Q3773]
MLAEVLRDNGYHEYRARLHALLEIPELASDFEIHTRITHGFAATWLVKLTELGVFTPVERDQIIPLRTLKSRIERDQPLT
VEESDRLFRSAHITAMAEAVFGDAAKAKRWLSKPKERFAGLTPMQMLTTQQGTTQVEEMLLQIAEGFGL

Nucleotide

• Length: 450 bp