Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) brnT-shpB/BrnT-BrnA
Location 1369639..1370212 Replicon chromosome
Accession NZ_OU745373
Organism Cardiobacterium sp. Marseille-Q4385

Toxin (Protein)


Gene name brnT Uniprot ID -
Locus tag LG374_RS06705 Protein ID WP_115612595.1
Coordinates 1369639..1369935 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name shpB Uniprot ID -
Locus tag LG374_RS06710 Protein ID WP_225756965.1
Coordinates 1369916..1370212 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LG374_RS06675 1364878..1365855 + 978 WP_225756960.1 NYN domain-containing protein -
LG374_RS06680 1365860..1367053 - 1194 WP_225756961.1 beta-ketoacyl-ACP synthase -
LG374_RS06685 1367050..1367499 - 450 WP_225756962.1 hypothetical protein -
LG374_RS06690 1367520..1368215 - 696 WP_225756963.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
LG374_RS06695 1368445..1368915 + 471 WP_225758006.1 EamA family transporter -
LG374_RS06700 1368905..1369642 + 738 WP_225756964.1 competence/damage-inducible protein A -
LG374_RS06705 1369639..1369935 + 297 WP_115612595.1 BrnT family toxin Toxin
LG374_RS06710 1369916..1370212 + 297 WP_225756965.1 BrnA antitoxin family protein Antitoxin
LG374_RS06715 1370299..1371486 + 1188 WP_225758007.1 acetate kinase -
LG374_RS06720 1371498..1373573 + 2076 WP_225756966.1 phosphate acetyltransferase -
LG374_RS06725 1373650..1373886 + 237 WP_225756967.1 twin-arginine translocase TatA/TatE family subunit -
LG374_RS06730 1373896..1374342 + 447 WP_225756968.1 Sec-independent protein translocase protein TatB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(7-88)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(32-91)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11646.28 Da        Isoelectric Point: 7.4192

>T294885 WP_115612595.1 NZ_OU745373:1369639-1369935 [Cardiobacterium sp. Marseille-Q4385]
MNYRFEWDDGKERINIRKHSIDFTMASTVFLDPLHQMVQDRIEGGEWRWQTIGIVKGQVVVLVAHTVVETDTMTCIRIIS
ARHATKKEQEYYYGRTYH

Download         Length: 297 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11318.66 Da        Isoelectric Point: 4.5393

>AT294885 WP_225756965.1 NZ_OU745373:1369916-1370212 [Cardiobacterium sp. Marseille-Q4385]
MGVLIIKDGEYPEFTPEQEAMLTKLAAMDDRDIDTSDIPELGDDFWRQAQRGHFRRREQLTIGIDSDILHWLRQQGGDYQ
ARLNAILRRVMQQESSGG

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References