Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2707753..2708410 Replicon chromosome
Accession NZ_OU659204
Organism Providencia alcalifaciens strain 2019-04-29291-1-1 isolate 2019-04-29291-1-1

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag LDO73_RS12435 Protein ID WP_224058187.1
Coordinates 2707753..2708163 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag LDO73_RS12440 Protein ID WP_036951240.1
Coordinates 2708144..2708410 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDO73_RS12415 (NVI2019_GHJFPKLH_02495) 2703727..2705460 - 1734 WP_224058180.1 single-stranded-DNA-specific exonuclease RecJ -
LDO73_RS12420 (NVI2019_GHJFPKLH_02496) 2705469..2706170 - 702 WP_224058181.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
LDO73_RS12425 (NVI2019_GHJFPKLH_02497) 2706189..2707091 - 903 WP_224058183.1 site-specific tyrosine recombinase XerD -
LDO73_RS12430 (NVI2019_GHJFPKLH_02498) 2707209..2707727 + 519 WP_224058185.1 flavodoxin FldB -
LDO73_RS12435 (NVI2019_GHJFPKLH_02499) 2707753..2708163 - 411 WP_224058187.1 protein YgfX Toxin
LDO73_RS12440 (NVI2019_GHJFPKLH_02500) 2708144..2708410 - 267 WP_036951240.1 FAD assembly factor SdhE Antitoxin
LDO73_RS12445 (NVI2019_GHJFPKLH_02501) 2708702..2709688 + 987 WP_224058189.1 tRNA-modifying protein YgfZ -
LDO73_RS12450 (NVI2019_GHJFPKLH_02502) 2709700..2710320 + 621 WP_224058191.1 HD domain-containing protein -
LDO73_RS12455 (NVI2019_GHJFPKLH_02503) 2710411..2711148 + 738 WP_224058193.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15471.43 Da        Isoelectric Point: 10.6257

>T294827 WP_224058187.1 NZ_OU659204:c2708163-2707753 [Providencia alcalifaciens]
VVLWKSNLSISWKTQLFSTCLHGVTGIILLVAPWAPGNSMIWLPLLVVLVASWAKSQKNISKVKGVAVLVNGNKLQWKKN
EWEIIKAPWCSRFGILLTLNALQGKPQKLRLWIAKDSVCEENWRNLNQLLLQYPDI

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10720.26 Da        Isoelectric Point: 4.9148

>AT294827 WP_036951240.1 NZ_OU659204:c2708410-2708144 [Providencia alcalifaciens]
IDINNKARIHWACRRGMRELDISIMPFFEYEYDELTDHDKRVFVRLLECPDPDLFNWLMNHGRPEDEELFSMIKLIQERN
KNRGPVEI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References