Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF-MazE
Location 2606912..2607543 Replicon chromosome
Accession NZ_OU659204
Organism Providencia alcalifaciens strain 2019-04-29291-1-1 isolate 2019-04-29291-1-1

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag LDO73_RS11980 Protein ID WP_224058070.1
Coordinates 2607175..2607543 (+) Length 123 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag LDO73_RS11975 Protein ID WP_224058069.1
Coordinates 2606912..2607175 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDO73_RS11960 (NVI2019_GHJFPKLH_02404) 2602343..2603374 + 1032 WP_224058067.1 ABC transporter substrate-binding protein -
LDO73_RS11965 (NVI2019_GHJFPKLH_02405) 2603623..2605701 + 2079 WP_211886162.1 iron ABC transporter permease -
LDO73_RS11970 (NVI2019_GHJFPKLH_02406) 2605718..2606758 + 1041 WP_224058068.1 ferric ABC transporter ATP-binding protein -
LDO73_RS11975 (NVI2019_GHJFPKLH_02407) 2606912..2607175 + 264 WP_224058069.1 antitoxin Antitoxin
LDO73_RS11980 (NVI2019_GHJFPKLH_02408) 2607175..2607543 + 369 WP_224058070.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
LDO73_RS11985 (NVI2019_GHJFPKLH_02409) 2607643..2611530 - 3888 WP_224058071.1 phosphoribosylformylglycinamidine synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(9-117)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13308.16 Da        Isoelectric Point: 6.6990

>T294826 WP_224058070.1 NZ_OU659204:2607175-2607543 [Providencia alcalifaciens]
MVKAKRPHKGQIWHINGDPVAGKEFKGPHYYLVVTDAQINTALGTSICVPITSGGSRARTQNVTVYLDGSSTDTGNITGC
ILCYQLRSLDLIARKATYSATLNEDIFEEVLSNIIDIIDPQI

Download         Length: 369 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9357.91 Da        Isoelectric Point: 6.2855

>AT294826 WP_224058069.1 NZ_OU659204:2606912-2607175 [Providencia alcalifaciens]
MSTTKLRQQGGAVVLTIPIEVANMAGWVVGMKLNIDAVGESICIKPVKRVARGRKSINELLSGIAKEEIKLLNSEVDDSD
PQGNEII

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References