294821

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 555411..556447 Replicon chromosome
Accession NZ_OU659204
Organism Providencia alcalifaciens strain 2019-04-29291-1-1 isolate 2019-04-29291-1-1

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag LDO73_RS02405 Protein ID WP_230089106.1
Coordinates 555411..555914 (-) Length 168 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag LDO73_RS02410 Protein ID WP_154602047.1
Coordinates 555986..556447 (-) Length 154 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDO73_RS02385 (NVI2019_GHJFPKLH_00478) 551149..552180 + 1032 WP_224060031.1 carbon-nitrogen hydrolase family protein -
LDO73_RS02390 (NVI2019_GHJFPKLH_00479) 552177..552932 + 756 WP_282560735.1 Asp/Glu racemase -
LDO73_RS02395 (NVI2019_GHJFPKLH_00480) 553018..553470 + 453 WP_224060032.1 MarR family transcriptional regulator -
LDO73_RS02400 (NVI2019_GHJFPKLH_00481) 553745..555391 + 1647 WP_224060033.1 Na+/H+ antiporter -
LDO73_RS02405 (NVI2019_GHJFPKLH_00482) 555411..555914 - 504 WP_230089106.1 PIN domain-containing protein Toxin
LDO73_RS02410 (NVI2019_GHJFPKLH_00483) 555986..556447 - 462 WP_154602047.1 helix-turn-helix domain-containing protein Antitoxin
LDO73_RS02415 (NVI2019_GHJFPKLH_00484) 556778..557194 + 417 WP_224060034.1 DUF4440 domain-containing protein -
LDO73_RS02420 (NVI2019_GHJFPKLH_00485) 557358..557663 + 306 WP_224060035.1 zinc ribbon domain-containing protein -
LDO73_RS02425 (NVI2019_GHJFPKLH_00486) 557700..558257 + 558 WP_224060036.1 methyltransferase -
LDO73_RS02430 (NVI2019_GHJFPKLH_00487) 558304..558924 - 621 WP_224060037.1 flavin reductase family protein -
LDO73_RS02435 (NVI2019_GHJFPKLH_00488) 559604..559948 + 345 WP_224060038.1 helix-turn-helix transcriptional regulator -
LDO73_RS02440 (NVI2019_GHJFPKLH_00489) 560079..560630 + 552 WP_224060039.1 fimbrial protein -
LDO73_RS02445 (NVI2019_GHJFPKLH_00490) 560775..561287 + 513 WP_224061120.1 type 1 fimbrial protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-91)

Antitoxin

Helix-turn-helix domain, group 17

(84-132)


Sequences

Toxin        


Download         Length: 168 a.a.        Molecular weight: 19086.04 Da        Isoelectric Point: 5.9969

>T294821 WP_230089106.1 NZ_OU659204:c555914-555411 [Providencia alcalifaciens]
MHLAITGLYQAKWTDTIQDEWQRNLLSNRPDLAQKQLIRTASLMNNALPDARVSQYEPLIEGIELPDLNDRHVVAAAIKC
HAKIIVTLNLKDFPKESMDQLEIEALHPDEFISDLFDLNHALALSAVRRQRLSLTKPEININEYFAALLRQGLPMTVKAL
EKYQSMI

Download         Length: 504 bp

Antitoxin


Download         Length: 154 a.a.        Molecular weight: 17032.65 Da        Isoelectric Point: 6.4930

>AT294821 WP_154602047.1 NZ_OU659204:c556447-555986 [Providencia alcalifaciens]
MTHSILNSMSLPAPKEIEAAVRGQRELATYLSTKLETQQISIKDADDNIHQIELPTSALTLLMAILGELAAGNAVQVVPV
HAELTTQEAANILNVSRPHMVKLLEEGRLPFHKTGRHRRILFADLMQFKAQREKESLQAMQALVDQSQELGLY

Download         Length: 462 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References