Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 136810..137332 Replicon plasmid 2
Accession NZ_OU659151
Organism Providencia alcalifaciens strain 2019-04-29290-1-7 isolate 2019-04-29290-1-7

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LDP49_RS19950 Protein ID WP_036974970.1
Coordinates 136810..137091 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LDP49_RS19955 Protein ID WP_036974972.1
Coordinates 137081..137332 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDP49_RS19950 (NVI2019_NGLDDFDA_03992) 136810..137091 - 282 WP_036974970.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LDP49_RS19955 (NVI2019_NGLDDFDA_03993) 137081..137332 - 252 WP_036974972.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LDP49_RS19960 (NVI2019_NGLDDFDA_03994) 137491..138072 - 582 WP_036982181.1 recombinase family protein -
LDP49_RS19965 (NVI2019_NGLDDFDA_03995) 138442..138960 + 519 WP_224120839.1 fimbrial protein -
LDP49_RS19970 (NVI2019_NGLDDFDA_03996) 139081..139581 + 501 WP_282564619.1 fimbrial protein -
LDP49_RS19975 (NVI2019_NGLDDFDA_03997) 139697..142198 + 2502 WP_224120841.1 fimbria/pilus outer membrane usher protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - prgK / prgI / sicA / spaS / spaQ / spaP / invC/sctN / invA / vopT / espC / papC / espC 1..153987 153987
- flank IS/Tn - - 137491..138072 581


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11028.01 Da        Isoelectric Point: 10.6508

>T294811 WP_036974970.1 NZ_OU659151:c137091-136810 [Providencia alcalifaciens]
MTYKLEFDRRALKEWQKLAPPIRNQFKKKLLERLENPCVPSAKLSGKNNRYKIKLRSLGYRLIYEVIDEKIILLVIAVGK
REGNTVYFSSNER

Download         Length: 282 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9116.31 Da        Isoelectric Point: 3.7550

>AT294811 WP_036974972.1 NZ_OU659151:c137332-137081 [Providencia alcalifaciens]
MTYQILSDTAASITDLKKNPMGTIAGGEGNPVAILNRNEPAFYCVPPELFAWFMELAEDAELNKIADERLESLDVVSVNI
DDL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References