Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2885325..2885982 Replicon chromosome
Accession NZ_OU659150
Organism Providencia alcalifaciens strain 2019-04-29290-1-7 isolate 2019-04-29290-1-7

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag LDP49_RS13900 Protein ID WP_006661186.1
Coordinates 2885325..2885735 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag LDP49_RS13905 Protein ID WP_036964213.1
Coordinates 2885716..2885982 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDP49_RS13880 (NVI2019_NGLDDFDA_02784) 2881299..2883032 - 1734 WP_036968251.1 single-stranded-DNA-specific exonuclease RecJ -
LDP49_RS13885 (NVI2019_NGLDDFDA_02785) 2883041..2883742 - 702 WP_006658051.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
LDP49_RS13890 (NVI2019_NGLDDFDA_02786) 2883761..2884663 - 903 WP_006658050.1 site-specific tyrosine recombinase XerD -
LDP49_RS13895 (NVI2019_NGLDDFDA_02787) 2884781..2885299 + 519 WP_006658049.1 flavodoxin FldB -
LDP49_RS13900 (NVI2019_NGLDDFDA_02788) 2885325..2885735 - 411 WP_006661186.1 protein YgfX Toxin
LDP49_RS13905 (NVI2019_NGLDDFDA_02789) 2885716..2885982 - 267 WP_036964213.1 FAD assembly factor SdhE Antitoxin
LDP49_RS13910 (NVI2019_NGLDDFDA_02790) 2886274..2887260 + 987 WP_006661184.1 tRNA-modifying protein YgfZ -
LDP49_RS13915 (NVI2019_NGLDDFDA_02791) 2887272..2887892 + 621 WP_006658045.1 HD domain-containing protein -
LDP49_RS13920 (NVI2019_NGLDDFDA_02792) 2887981..2890857 - 2877 WP_224120245.1 aminomethyl-transferring glycine dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15437.35 Da        Isoelectric Point: 10.6963

>T294809 WP_006661186.1 NZ_OU659150:c2885735-2885325 [Providencia alcalifaciens]
VVLWKSNLSISWKTQLFSTSLHVGAGIILLVAPWEPGNSMIWLPLLVILVASWAKSQKNISKVKGVAVLVNGNKLQWKKN
EWEIIKAPWCSRCGILLTLKALQGKPQKLRLWVAKDSVSEENWRNLNQLLLQYPDI

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10734.28 Da        Isoelectric Point: 4.9148

>AT294809 WP_036964213.1 NZ_OU659150:c2885982-2885716 [Providencia alcalifaciens]
IDINNKARIHWACRRGMRELDISIMPFFEYEYDELTDHDKRIFVRLLECPDPDLFNWLMNHGRPEDEELFSMIKLIQERN
KNRGPVEI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References