Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2356919..2357576 Replicon chromosome
Accession NZ_OU659130
Organism Providencia alcalifaciens strain 2019-04-28370-1-5 isolate 2019-04-28370-1-5

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag LDO77_RS11325 Protein ID WP_006661186.1
Coordinates 2356919..2357329 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag LDO77_RS11330 Protein ID WP_036964213.1
Coordinates 2357310..2357576 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDO77_RS11305 (NVI2019_OHEONHNH_02275) 2352893..2354626 - 1734 WP_036968251.1 single-stranded-DNA-specific exonuclease RecJ -
LDO77_RS11310 (NVI2019_OHEONHNH_02276) 2354635..2355336 - 702 WP_006658051.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
LDO77_RS11315 (NVI2019_OHEONHNH_02277) 2355355..2356257 - 903 WP_224050460.1 site-specific tyrosine recombinase XerD -
LDO77_RS11320 (NVI2019_OHEONHNH_02278) 2356375..2356893 + 519 WP_006658049.1 flavodoxin FldB -
LDO77_RS11325 (NVI2019_OHEONHNH_02279) 2356919..2357329 - 411 WP_006661186.1 protein YgfX Toxin
LDO77_RS11330 (NVI2019_OHEONHNH_02280) 2357310..2357576 - 267 WP_036964213.1 FAD assembly factor SdhE Antitoxin
LDO77_RS11335 (NVI2019_OHEONHNH_02281) 2357868..2358854 + 987 WP_036968245.1 tRNA-modifying protein YgfZ -
LDO77_RS11340 (NVI2019_OHEONHNH_02282) 2358866..2359486 + 621 WP_224050461.1 HD domain-containing protein -
LDO77_RS11345 (NVI2019_OHEONHNH_02283) 2359574..2362450 - 2877 WP_224050462.1 aminomethyl-transferring glycine dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15437.35 Da        Isoelectric Point: 10.6963

>T294801 WP_006661186.1 NZ_OU659130:c2357329-2356919 [Providencia alcalifaciens]
VVLWKSNLSISWKTQLFSTSLHVGAGIILLVAPWEPGNSMIWLPLLVILVASWAKSQKNISKVKGVAVLVNGNKLQWKKN
EWEIIKAPWCSRCGILLTLKALQGKPQKLRLWVAKDSVSEENWRNLNQLLLQYPDI

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10734.28 Da        Isoelectric Point: 4.9148

>AT294801 WP_036964213.1 NZ_OU659130:c2357576-2357310 [Providencia alcalifaciens]
IDINNKARIHWACRRGMRELDISIMPFFEYEYDELTDHDKRIFVRLLECPDPDLFNWLMNHGRPEDEELFSMIKLIQERN
KNRGPVEI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References