Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2845586..2846243 Replicon chromosome
Accession NZ_OU659113
Organism Providencia alcalifaciens strain 2019-04-27799-1-2 isolate 2019-04-27799-1-2

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag LDO34_RS13790 Protein ID WP_006661186.1
Coordinates 2845586..2845996 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag LDO34_RS13795 Protein ID WP_036964213.1
Coordinates 2845977..2846243 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDO34_RS13770 (NVI2019_KOLGMIGM_02771) 2841560..2843293 - 1734 WP_036968251.1 single-stranded-DNA-specific exonuclease RecJ -
LDO34_RS13775 (NVI2019_KOLGMIGM_02772) 2843302..2844003 - 702 WP_006658051.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
LDO34_RS13780 (NVI2019_KOLGMIGM_02773) 2844022..2844924 - 903 WP_224050460.1 site-specific tyrosine recombinase XerD -
LDO34_RS13785 (NVI2019_KOLGMIGM_02774) 2845042..2845560 + 519 WP_006658049.1 flavodoxin FldB -
LDO34_RS13790 (NVI2019_KOLGMIGM_02775) 2845586..2845996 - 411 WP_006661186.1 protein YgfX Toxin
LDO34_RS13795 (NVI2019_KOLGMIGM_02776) 2845977..2846243 - 267 WP_036964213.1 FAD assembly factor SdhE Antitoxin
LDO34_RS13800 (NVI2019_KOLGMIGM_02777) 2846535..2847521 + 987 WP_036968245.1 tRNA-modifying protein YgfZ -
LDO34_RS13805 (NVI2019_KOLGMIGM_02778) 2847533..2848153 + 621 WP_224050461.1 HD domain-containing protein -
LDO34_RS13810 (NVI2019_KOLGMIGM_02779) 2848241..2851117 - 2877 WP_224050462.1 aminomethyl-transferring glycine dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15437.35 Da        Isoelectric Point: 10.6963

>T294776 WP_006661186.1 NZ_OU659113:c2845996-2845586 [Providencia alcalifaciens]
VVLWKSNLSISWKTQLFSTSLHVGAGIILLVAPWEPGNSMIWLPLLVILVASWAKSQKNISKVKGVAVLVNGNKLQWKKN
EWEIIKAPWCSRCGILLTLKALQGKPQKLRLWVAKDSVSEENWRNLNQLLLQYPDI

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10734.28 Da        Isoelectric Point: 4.9148

>AT294776 WP_036964213.1 NZ_OU659113:c2846243-2845977 [Providencia alcalifaciens]
IDINNKARIHWACRRGMRELDISIMPFFEYEYDELTDHDKRIFVRLLECPDPDLFNWLMNHGRPEDEELFSMIKLIQERN
KNRGPVEI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References