Detailed information of TA system TA294772

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): sdenTA/AbiEii(toxin)
• Location: 366700..368140
• Replicon: chromosome
• Accession: NZ_OU594967
• Organism: Celerinatantimonas diazotrophica isolate CEDIAZO1

Toxin (Protein)

• Gene name: sdenT
• Uniprot ID: -
• Locus tag: LDO33_RS01725
• Protein ID: WP_131914392.1
• Coordinates: 367253..368140 (+)
• Length: 296 a.a.

Antitoxin (Protein)

• Gene name: sdenA
• Uniprot ID: -
• Locus tag: LDO33_RS01720
• Protein ID: WP_131914393.1
• Coordinates: 366700..367224 (+)
• Length: 175 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LDO33_RS01690 (CEDIAZO_00336)	362008..362946	+	939	WP_131914398.1	LysR family transcriptional regulator	-
LDO33_RS01695 (CEDIAZO_00337)	363382..363522	-	141	WP_165872818.1	hypothetical protein	-
LDO33_RS01700 (CEDIAZO_00338)	363587..364501	-	915	WP_131914397.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	-
LDO33_RS01705 (CEDIAZO_00339)	364508..365281	-	774	WP_131914396.1	type IV toxin-antitoxin system AbiEi family antitoxin	-
LDO33_RS01710 (CEDIAZO_00340)	365513..365962	-	450	WP_263433858.1	class I SAM-dependent methyltransferase	-
LDO33_RS01715	366093..366350	-	258	Protein_338	2Fe-2S iron-sulfur cluster-binding protein	-
LDO33_RS01720 (CEDIAZO_00342)	366700..367224	+	525	WP_131914393.1	hypothetical protein	Antitoxin
LDO33_RS01725 (CEDIAZO_00343)	367253..368140	+	888	WP_131914392.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
LDO33_RS01730	368305..368526	+	222	Protein_341	hypothetical protein	-
LDO33_RS01735 (CEDIAZO_00344)	368579..369439	-	861	WP_131914391.1	YicC/YloC family endoribonuclease	-
LDO33_RS01740 (CEDIAZO_00345)	369571..370290	+	720	WP_131914390.1	ribonuclease PH	-
LDO33_RS01745 (CEDIAZO_00346)	370307..370951	+	645	WP_131914389.1	orotate phosphoribosyltransferase	-
LDO33_RS01750 (CEDIAZO_00347)	371097..371252	-	156	WP_165872816.1	hypothetical protein	-
LDO33_RS01755 (CEDIAZO_00348)	371326..371481	-	156	WP_165872815.1	hypothetical protein	-
LDO33_RS01760 (CEDIAZO_00349)	371555..371710	-	156	WP_165872814.1	hypothetical protein	-
LDO33_RS01765 (CEDIAZO_00350)	371784..371939	-	156	WP_165872814.1	hypothetical protein	-
LDO33_RS01770 (CEDIAZO_00351)	372012..372167	-	156	WP_165872814.1	hypothetical protein	-
LDO33_RS01775 (CEDIAZO_00352)	372241..372396	-	156	WP_165872814.1	hypothetical protein	-
LDO33_RS01780 (CEDIAZO_00353)	372469..372624	-	156	WP_165872814.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (37-258)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 296 a.a.
• Molecular weight: 34209.17 Da
• Isoelectric Point: 5.2699

>T294772 WP_131914392.1 NZ_OU594967:367253-368140 [Celerinatantimonas diazotrophica]
MLKQQIRQIVQSNPDYAAVTPVIEKEILHHDIMDVLIKQGVLQRLTFIGDTSLRMCYNSSRLSEDLDFNGGDDFKPSEFE
GLESEIQTYIQNKYETEVWVSKPSGEQQGNTVSWKISIVKEPNRPDLPRQKMHIDVCAMPSFDIEKRPLINHYDIVVPTE
GILVPVQSLQEILADKLIALAYRARRIKPRDIWDIVWIKQRGIDLSKVLVEKKLNARHKQTDDFRQMLSTALAKLMLEDE
VHNDFNMEMSRFIPKQIKERTLDNPEYWTYVQGEVNAIASELLHDDTAKNPFDMG

Nucleotide

• Length: 888 bp

Antitoxin

Protein

• Length: 175 a.a.
• Molecular weight: 19457.68 Da
• Isoelectric Point: 9.6781

>AT294772 WP_131914393.1 NZ_OU594967:366700-367224 [Celerinatantimonas diazotrophica]
MAKSDELLSALAKAVNAGGGVHSATELAFMLGEPCDPAFRKFLADSVKKGLLRRVVKGFYESMITPPEPETAIYKIIKKL
RSGVLNYISLESQLSYTGDISQIMMGRVTVVTKGRSGCFDTPYGVIEFTHTKKPVEQIALHLYYDSDIKMYRANRAQALA
DLKHCRRNLHMLER

Nucleotide

• Length: 525 bp