Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1634704..1635338 Replicon chromosome
Accession NZ_LT996886
Organism Tessaracoccus timonensis strain Marseille-P5995

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag DHT94_RS07760 Protein ID WP_108871336.1
Coordinates 1634940..1635338 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag DHT94_RS07755 Protein ID WP_108871335.1
Coordinates 1634704..1634946 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DHT94_RS07740 1631532..1632701 - 1170 WP_108871332.1 MFS transporter -
DHT94_RS07745 1632698..1633111 - 414 WP_108871333.1 hypothetical protein -
DHT94_RS07750 1633275..1634669 + 1395 WP_108871334.1 amidase -
DHT94_RS07755 1634704..1634946 + 243 WP_108871335.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
DHT94_RS07760 1634940..1635338 + 399 WP_108871336.1 type II toxin-antitoxin system VapC family toxin Toxin
DHT94_RS07765 1635386..1636678 + 1293 WP_108871337.1 thymidine phosphorylase -
DHT94_RS13290 1636675..1637295 + 621 WP_159087448.1 hypothetical protein -
DHT94_RS07775 1637496..1637867 + 372 WP_108871339.1 hypothetical protein -
DHT94_RS07780 1637877..1638749 - 873 WP_159087449.1 aminotransferase class IV -
DHT94_RS07790 1639156..1640061 - 906 WP_108871341.1 metallophosphoesterase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

SpoVT-AbrB domain

(9-44)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14938.02 Da        Isoelectric Point: 7.1362

>T294439 WP_108871336.1 NZ_LT996886:1634940-1635338 [Tessaracoccus timonensis]
MVTYLLDTSIWIELLRGNESVVQRMQRCSPRDIRLSPIVQGELETGRQLSQSADQAEMLEWVYHSFPRNAFGDTVARQCG
VVRAQLRRAGTPIGVNDTWIAAEALAHGQTVVTANERDFRRVPGLKVENWMV

Download         Length: 399 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9044.13 Da        Isoelectric Point: 4.0808

>AT294439 WP_108871335.1 NZ_LT996886:1634704-1634946 [Tessaracoccus timonensis]
MTPRTTTVFKSGNSQAVRIPKDLAFSTDKVTIEVDGDALILRPQPLTMQEFLDGLPRHPGAFENFPDFEDEIDEEPVPQW

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References