Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 791656..792338 Replicon chromosome
Accession NZ_LT996886
Organism Tessaracoccus timonensis strain Marseille-P5995

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag DHT94_RS03970 Protein ID WP_108870684.1
Coordinates 791907..792338 (+) Length 144 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag DHT94_RS03965 Protein ID WP_108870683.1
Coordinates 791656..791907 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DHT94_RS03935 787423..787956 + 534 WP_197709372.1 fumarate hydratase -
DHT94_RS03940 788072..789073 - 1002 WP_197709373.1 NADP-dependent oxidoreductase -
DHT94_RS03945 789066..789470 + 405 WP_005885516.1 helix-turn-helix transcriptional regulator -
DHT94_RS13210 789913..790317 + 405 WP_159087358.1 hypothetical protein -
DHT94_RS03955 790393..790713 + 321 WP_197709374.1 hypothetical protein -
DHT94_RS03960 791316..791522 - 207 WP_159087359.1 hypothetical protein -
DHT94_RS03965 791656..791907 + 252 WP_108870683.1 antitoxin Antitoxin
DHT94_RS03970 791907..792338 + 432 WP_108870684.1 PIN domain-containing protein Toxin
DHT94_RS03975 792467..793216 - 750 WP_159087360.1 ABC transporter permease -
DHT94_RS03980 793399..793614 + 216 WP_108870686.1 mandelate racemase -
DHT94_RS03985 793722..794483 + 762 WP_108872330.1 sulfite exporter TauE/SafE family protein -
DHT94_RS03990 794524..795633 - 1110 WP_197709481.1 zinc-binding dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(1-135)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 144 a.a.        Molecular weight: 15606.75 Da        Isoelectric Point: 5.8960

>T294438 WP_108870684.1 NZ_LT996886:791907-792338 [Tessaracoccus timonensis]
MLLVDTNVLIYAVNASSAHHDASRTWFLHELQSGTDVVGLPWVSLLGFIRISTHSHILEHPLSPEEAMSVVHAWLNHPRV
VTPEPSPRHAALLAGLLAESGTAGNLTNDAHLAALALELDATMVTFDRDFARFGVRVLVPEHE

Download         Length: 432 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9252.40 Da        Isoelectric Point: 5.5941

>AT294438 WP_108870683.1 NZ_LT996886:791656-791907 [Tessaracoccus timonensis]
MRTTLTLDPDVAKLLEEEMAKRQTSFKRVVNDALRRGLGSHHDADFTFPSFDMGSANADLTHATRLAADMEDEALAFKLT
QGR

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References