Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 1602241..1603154 Replicon chromosome
Accession NZ_LT992502
Organism Enterobacter bugandensis isolate EB-247

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag DG357_RS07740 Protein ID WP_088204937.1
Coordinates 1602241..1602714 (-) Length 158 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag DG357_RS07745 Protein ID WP_045261776.1
Coordinates 1602711..1603154 (-) Length 148 a.a.

Genomic Context

DG357_RS07720DG357_RS07725DG357_RS07730DG357_RS07735DG357_RS07740DG357_RS07745DG357_RS07750DG357_RS07755DG357_RS07760
Location: 1598400..1599710 (1311 bp)
Type: Others
Protein ID: WP_088204934.1
Location: 1599707..1600642 (936 bp)
Type: Others
Protein ID: WP_088204935.1
Location: 1600656..1601654 (999 bp)
Type: Others
Protein ID: WP_045261779.1
Location: 1601664..1602218 (555 bp)
Type: Others
Protein ID: WP_088204936.1
Location: 1602241..1602714 (474 bp)
Type: Toxin
Protein ID: WP_088204937.1
Location: 1602711..1603154 (444 bp)
Type: Antitoxin
Protein ID: WP_045261776.1
Location: 1603772..1603990 (219 bp)
Type: Others
Protein ID: WP_002211347.1
Location: 1604275..1604979 (705 bp)
Type: Others
Protein ID: WP_041910636.1
Location: 1605025..1606746 (1722 bp)
Type: Others
Protein ID: WP_088204938.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
DG357_RS077201598400..1599710+1311WP_088204934.1type I-F CRISPR-associated protein Csy1-
DG357_RS077251599707..1600642+936WP_088204935.1type I-F CRISPR-associated protein Csy2-
DG357_RS077301600656..1601654+999WP_045261779.1type I-F CRISPR-associated protein Csy3-
DG357_RS077351601664..1602218+555WP_088204936.1type I-F CRISPR-associated endoribonuclease Cas6/Csy4-
DG357_RS077401602241..1602714-474WP_088204937.1RES domain-containing proteinToxin
DG357_RS077451602711..1603154-444WP_045261776.1DUF2384 domain-containing proteinAntitoxin
DG357_RS077501603772..1603990-219WP_002211347.1translation initiation factor IF-1-
DG357_RS077551604275..1604979-705WP_041910636.1leucyl/phenylalanyl-tRNA--protein transferase-
DG357_RS077601605025..1606746-1722WP_088204938.1cysteine/glutathione ABC transporter ATP-binding protein/permease CydC-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-147)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(30-90)


Sequences

Toxin        


Download         Length: 158 a.a.        Molecular weight: 17531.88 Da        Isoelectric Point: 5.0700

>T294425 WP_088204937.1 NZ_LT992502:c1602714-1602241 [Enterobacter bugandensis]
MIFYRLVTGRYASEAWSGSGANQYGGRWNHKGHPAVYVSTSISLASLEILVHIRKDTVLNQYQLFSIDIPDDQIDYLDKA
WLPEDWQENPAPVSTMDLGTGWLQASSALALILPSCIIPYENNAILNPLHPAFHTALSSVQQMPFIFDTRLAEKTAP

Download         Length: 474 bp

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16365.72 Da        Isoelectric Point: 8.5886

>AT294425 WP_045261776.1 NZ_LT992502:c1603154-1602711 [Enterobacter bugandensis]
MRTWIPAKKPADNALWRYAGLPANRGMRLIEFLNQGLPVSVLDNIHEWTAMSKADILRVTGINERNVARRKSAGRTLTPD
ESERVARFVRVLDAAVDYFGSKEEAWNWLQSPVRGLGNVAPVDLIATETGALEVTDLIGRLEHGVFA

Download         Length: 444 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References