294423

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 504713..505229 Replicon chromosome
Accession NZ_LT992502
Organism Enterobacter bugandensis isolate EB-247

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DG357_RS02475 Protein ID WP_088204684.1
Coordinates 504945..505229 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A8E1RL94
Locus tag DG357_RS02470 Protein ID WP_023331889.1
Coordinates 504713..504955 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DG357_RS02455 500803..501543 + 741 WP_041911457.1 KDGP aldolase family protein -
DG357_RS02460 501569..502705 + 1137 WP_088204685.1 lactonase family protein -
DG357_RS02465 502725..504635 + 1911 WP_048999489.1 BglG family transcription antiterminator -
DG357_RS02470 504713..504955 + 243 WP_023331889.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
DG357_RS02475 504945..505229 + 285 WP_088204684.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DG357_RS02480 505233..505697 - 465 WP_088204683.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
DG357_RS02485 505783..507921 - 2139 WP_048960133.1 anaerobic ribonucleoside-triphosphate reductase -
DG357_RS02490 508291..508863 - 573 WP_088204682.1 fructose PTS transporter subunit IIA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-69)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10991.91 Da        Isoelectric Point: 10.0526

>T294423 WP_088204684.1 NZ_LT992502:504945-505229 [Enterobacter bugandensis]
MIYELEFDPRALKEWHKLGDTVKCQFKKKLADVLVNPRIESARLHGLSDCYKIKLRSLGYRLVYQVQDNVVTVFVIAIGK
REKSAVYHEANKRL

Download         Length: 285 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9030.41 Da        Isoelectric Point: 4.7719

>AT294423 WP_023331889.1 NZ_LT992502:504713-504955 [Enterobacter bugandensis]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRMPVKTVTISDSEDELIQTVRERLANPQKGIKVSLDDL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References