Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 3008967..3010242 Replicon chromosome
Accession NC_021237
Organism Pseudomonas protegens CHA0

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PFLCHA0_RS13775 Protein ID WP_041752203.1
Coordinates 3009643..3010242 (+) Length 200 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PFLCHA0_RS13770 Protein ID WP_041752748.1
Coordinates 3008967..3009524 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PFLCHA0_RS13740 3004219..3004869 + 651 WP_041752197.1 DUF2239 family protein -
PFLCHA0_RS13745 3004957..3005577 + 621 WP_041752198.1 LysE family translocator -
PFLCHA0_RS13750 3005623..3006210 - 588 WP_011060980.1 inclusion body family protein -
PFLCHA0_RS13755 3006622..3007809 + 1188 WP_041752200.1 PrpF protein -
PFLCHA0_RS13760 3007988..3008455 - 468 WP_051167106.1 hypothetical protein -
PFLCHA0_RS13765 3008436..3008777 - 342 WP_041752202.1 low molecular weight protein tyrosine phosphatase family protein -
PFLCHA0_RS13770 3008967..3009524 + 558 WP_041752748.1 helix-turn-helix domain-containing protein Antitoxin
PFLCHA0_RS13775 3009643..3010242 + 600 WP_041752203.1 HD domain-containing protein Toxin
PFLCHA0_RS13780 3010457..3012637 + 2181 WP_015635385.1 catalase/peroxidase HPI -
PFLCHA0_RS13785 3012848..3013306 + 459 WP_015635386.1 hypothetical protein -
PFLCHA0_RS13790 3013498..3013926 - 429 WP_011060992.1 hypothetical protein -
PFLCHA0_RS13795 3014161..3015075 + 915 WP_015635387.1 SGNH/GDSL hydrolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

5'-deoxynucleotidase YfbR/HDDC2

(8-147)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-47)


Sequences

Toxin        


Download         Length: 200 a.a.        Molecular weight: 22463.25 Da        Isoelectric Point: 5.3128

>T29440 WP_041752203.1 NC_021237:3009643-3010242 [Pseudomonas protegens CHA0]
MNSELLSGRLDFLREAEKLKDVLRSAHTSSGRQESTAEHSWRLCLMALLFEDQLGDLDLLRVLKLCIVHDLGEAIHGDIP
AVAQAAHPDKSQQERDDLQLLARALDAPAREHLLELWDEYEGAASNEARAVKALDKLETLLQHTQGQNPAGFDYRFNLGY
GRRYTDASPLFQALRQQIDIDTQRCLDAQAQAAVQHRLR

Download         Length: 600 bp

>T29440 NC_021237:3009643-3010242 [Pseudomonas protegens CHA0]
ATGAACAGTGAACTTCTCAGTGGCCGCCTCGACTTTCTCCGTGAAGCGGAAAAACTCAAGGACGTGCTGCGCAGCGCCCA
CACCTCCAGCGGCCGCCAGGAAAGCACGGCCGAGCACAGCTGGCGCCTATGCCTGATGGCGCTGCTGTTCGAAGACCAAC
TGGGGGACCTGGACCTGCTGCGGGTGCTGAAACTGTGCATCGTCCACGACCTGGGGGAGGCCATTCACGGCGACATCCCG
GCGGTGGCCCAGGCTGCCCACCCGGACAAGAGCCAGCAGGAGCGCGACGACCTGCAACTGCTGGCCCGAGCCCTGGACGC
CCCGGCCCGCGAGCACCTGCTGGAGCTGTGGGACGAATACGAAGGCGCCGCCAGCAACGAGGCGCGCGCGGTCAAGGCCC
TGGACAAGCTGGAAACCCTGCTGCAACACACCCAGGGCCAGAACCCGGCGGGTTTCGACTACCGCTTCAACCTCGGCTAC
GGCCGCCGCTACACCGACGCCAGCCCGCTGTTCCAAGCCCTGCGCCAGCAGATCGACATCGACACCCAGCGTTGCCTGGA
CGCCCAGGCTCAGGCCGCGGTTCAGCATCGGCTGCGCTAA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20497.44 Da        Isoelectric Point: 7.0311

>AT29440 WP_041752748.1 NC_021237:3008967-3009524 [Pseudomonas protegens CHA0]
MSVALFTSPHLGLALRRWRLLHRVKQQHAAELFGVAQSSISRWENGRQIMEPAERARLEQLLAANLSAAADQALARLVND
SPRAVHLVCDLTHRLLACSATRAGQFGVPLSELLGQSLWGFCTEEITRKEAALDDLGWREVLEPPSLEFFSGHNDSAIVP
IAPSQCRWTRLNLSDGNAVRLVETL

Download         Length: 558 bp

>AT29440 NC_021237:3008967-3009524 [Pseudomonas protegens CHA0]
ATGTCCGTAGCTCTGTTCACCTCCCCCCATCTGGGCCTGGCCCTCAGGCGCTGGCGCCTGTTGCACCGGGTCAAGCAGCA
GCACGCCGCCGAACTGTTCGGCGTGGCGCAGTCGAGCATTTCCCGTTGGGAAAACGGCCGGCAGATCATGGAACCGGCCG
AGCGTGCGCGCCTGGAACAACTGCTGGCGGCCAACCTCAGCGCCGCCGCCGACCAGGCCCTGGCGCGGCTGGTGAACGAC
AGCCCGCGCGCCGTGCACCTGGTGTGCGACCTGACCCACCGCCTGCTGGCCTGTTCCGCCACCCGCGCCGGGCAGTTCGG
CGTGCCCTTGAGTGAGCTGCTGGGCCAGTCCCTGTGGGGCTTTTGCACCGAGGAAATCACCCGCAAGGAAGCCGCCCTGG
ATGACCTGGGCTGGCGCGAAGTACTGGAGCCGCCGTCCCTGGAATTCTTCAGCGGCCACAACGATTCGGCCATCGTGCCC
ATCGCCCCCAGCCAGTGCCGCTGGACCCGCCTCAACCTCTCTGACGGCAACGCCGTGCGGCTGGTGGAAACCCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References