Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 1243228..1243852 Replicon chromosome
Accession NC_021215
Organism Helicobacter pylori UM032

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag K747_RS06145 Protein ID WP_000916178.1
Coordinates 1243586..1243852 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag K747_RS06140 Protein ID WP_015644924.1
Coordinates 1243228..1243605 (+) Length 126 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K747_RS06115 1238324..1239436 + 1113 WP_015644921.1 hydrogenase formation protein HypD -
K747_RS06120 1239387..1240037 - 651 Protein_1165 hypothetical protein -
K747_RS06135 1240429..1242654 + 2226 WP_015644923.1 Hop family adhesin BabA -
K747_RS06140 1243228..1243605 + 378 WP_015644924.1 hypothetical protein Antitoxin
K747_RS06145 1243586..1243852 + 267 WP_000916178.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
K747_RS06150 1243957..1244481 - 525 WP_001120212.1 acyl-CoA thioesterase -
K747_RS06155 1244622..1245470 + 849 WP_015644925.1 SDR family oxidoreductase -
K747_RS06160 1245463..1246443 + 981 WP_015644926.1 iron ABC transporter permease -
K747_RS06165 1246443..1247210 + 768 WP_000242365.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10273.15 Da        Isoelectric Point: 9.9840

>T29430 WP_000916178.1 NC_021215:1243586-1243852 [Helicobacter pylori UM032]
VLKLNLKKSFQKDFDKLLLNGFDDSVLNKVILSLRKKEPLDPQFQDHALKGKWKPFRECHIKADILLVYLVRGDELILVR
LGSHSELF

Download         Length: 267 bp

>T29430 NC_021215:1243586-1243852 [Helicobacter pylori UM032]
GTGTTGAAACTCAACCTTAAAAAATCTTTTCAAAAAGATTTTGATAAATTACTTTTGAATGGGTTTGATGATAGCGTTTT
GAATAAGGTCATTCTGTCTTTGAGAAAAAAAGAACCGCTAGACCCACAATTTCAAGATCATGCTTTAAAGGGAAAGTGGA
AACCTTTTAGGGAATGCCACATCAAAGCTGATATTTTACTTGTGTATTTGGTGAGAGGTGATGAGCTTATTTTAGTAAGA
CTAGGCAGTCATAGCGAGCTGTTTTAA

Antitoxin


Download         Length: 126 a.a.        Molecular weight: 14775.81 Da        Isoelectric Point: 9.4267

>AT29430 WP_015644924.1 NC_021215:1243228-1243605 [Helicobacter pylori UM032]
MPNSPTKKDYTRYSEKQLFNLINQLEQKIKRMQNDRASFKEKMAKELEKRDQNFKDKIDALNKLLQKISQAFDDKRDCCL
GRKIPNLETQQAMRDALNKETDLIVEDFSSYSDERKRALGVETQP

Download         Length: 378 bp

>AT29430 NC_021215:1243228-1243605 [Helicobacter pylori UM032]
ATGCCTAATTCTCCCACCAAAAAAGACTACACACGATACAGCGAAAAACAGCTTTTTAACTTAATCAACCAATTAGAGCA
AAAGATCAAAAGGATGCAAAATGATAGAGCTTCTTTTAAAGAAAAAATGGCTAAAGAATTGGAAAAAAGGGATCAAAACT
TTAAGGATAAAATAGACGCATTAAATAAACTCTTGCAAAAAATCAGCCAAGCTTTTGATGATAAAAGAGATTGTTGTTTG
GGGCGCAAGATCCCAAACCTTGAAACGCAACAAGCCATGAGAGATGCGCTTAACAAAGAAACTGATTTGATTGTTGAGGA
TTTTTCTAGTTATAGCGATGAAAGAAAAAGGGCGTTAGGTGTTGAAACTCAACCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References