Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 4657826..4658327 Replicon chromosome
Accession NC_021184
Organism Desulfotomaculum gibsoniae DSM 7213

Toxin (Protein)


Gene name yoeB Uniprot ID R4KM89
Locus tag DESGI_RS21735 Protein ID WP_006522357.1
Coordinates 4657826..4658080 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID R4KT76
Locus tag DESGI_RS21740 Protein ID WP_006522356.1
Coordinates 4658073..4658327 (-) Length 85 a.a.

Genomic Context

DESGI_RS21725DESGI_RS21730DESGI_RS21735DESGI_RS21740DESGI_RS21745DESGI_RS21750
Location: 4655935..4657062 (1128 bp)
Type: Others
Protein ID: WP_006522359.1
Location: 4657158..4657643 (486 bp)
Type: Others
Protein ID: WP_006522358.1
Location: 4657826..4658080 (255 bp)
Type: Toxin
Protein ID: WP_006522357.1
Location: 4658073..4658327 (255 bp)
Type: Antitoxin
Protein ID: WP_006522356.1
Location: 4658499..4660211 (1713 bp)
Type: Others
Protein ID: WP_006522355.1
Location: 4660400..4661503 (1104 bp)
Type: Others
Protein ID: WP_006522354.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
DESGI_RS217254655935..4657062-1128WP_006522359.1efflux RND transporter periplasmic adaptor subunit-
DESGI_RS217304657158..4657643-486WP_006522358.1MarR family transcriptional regulator-
DESGI_RS217354657826..4658080-255WP_006522357.1Txe/YoeB family addiction module toxinToxin
DESGI_RS217404658073..4658327-255WP_006522356.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
DESGI_RS217454658499..4660211-1713WP_006522355.1copper amine oxidase-
DESGI_RS217504660400..4661503-1104WP_006522354.1TolC family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10042.34 Da        Isoelectric Point: 8.0293

>T29419 WP_006522357.1 NC_021184:c4658080-4657826 [Desulfallas gibsoniae DSM 7213]
MNKIFSDVAWQHYLYWQSEDKKILKKVNELLRDIDRNGNEGLGKPEPLKNELSGYWSRRITDVHRLIYSIDNDNIYIASC
RGHY

Download         Length: 255 bp

>T29419 NC_021184:c4658080-4657826 [Desulfallas gibsoniae DSM 7213]
ATGAATAAAATCTTTTCGGATGTAGCATGGCAGCATTACTTGTATTGGCAATCAGAGGACAAAAAAATATTAAAGAAAGT
CAATGAGCTATTACGAGATATTGATAGAAATGGAAATGAAGGATTGGGCAAGCCGGAGCCACTGAAAAATGAATTATCCG
GATATTGGAGTCGCCGTATTACTGATGTTCATCGACTAATATATAGTATTGATAATGACAATATTTATATAGCTAGTTGC
AGAGGTCACTATTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9912.28 Da        Isoelectric Point: 7.9383

>AT29419 WP_006522356.1 NC_021184:c4658327-4658073 [Desulfallas gibsoniae DSM 7213]
MIATSYSSVRQNFKKYCDKAVNDFETIIITRERGENVVMLSEAEYNNLLENLYVRSNPKYYNELLQSIEQLKKGKGKKRE
LLDE

Download         Length: 255 bp

>AT29419 NC_021184:c4658327-4658073 [Desulfallas gibsoniae DSM 7213]
ATGATAGCAACAAGCTATTCGTCTGTAAGGCAAAATTTTAAAAAATATTGTGACAAGGCTGTAAACGATTTTGAAACAAT
TATTATTACTCGTGAACGTGGCGAGAATGTAGTTATGCTATCCGAAGCAGAGTATAATAACCTTTTAGAAAATCTCTATG
TGAGAAGTAATCCAAAATACTATAACGAACTTTTACAGTCTATAGAGCAATTAAAAAAAGGCAAGGGAAAGAAAAGAGAA
TTGCTTGATGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBR4KM89

Antitoxin

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Source
ID
Structure
AlphaFold DBR4KT76

References