294083

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsaAT/-
Location 2894096..2894572 Replicon chromosome
Accession NZ_LT992460
Organism Staphylococcus aureus isolate 9_LA_281

Toxin (Protein)


Gene name TsaT Uniprot ID T1Y7S2
Locus tag DXE39_RS15045 Protein ID WP_000052076.1
Coordinates 2894384..2894572 (+) Length 63 a.a.

Antitoxin (Protein)


Gene name TsaA Uniprot ID T1Y6P8
Locus tag DXE39_RS15040 Protein ID WP_001059690.1
Coordinates 2894096..2894356 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DXE39_RS15005 2889494..2890210 - 717 WP_000150026.1 type I 3-dehydroquinate dehydratase -
DXE39_RS15010 2890358..2890780 + 423 WP_000974452.1 organic hydroperoxide resistance protein -
DXE39_RS15015 2891179..2891673 + 495 WP_000569881.1 GNAT family N-acetyltransferase -
DXE39_RS15020 2891822..2892439 + 618 WP_000255562.1 LysE/ArgO family amino acid transporter -
DXE39_RS15025 2892512..2893093 - 582 WP_001140696.1 phosphoglycerate mutase family protein -
DXE39_RS15030 2893318..2893554 + 237 WP_000368687.1 hypothetical protein -
DXE39_RS15035 2893551..2893754 - 204 WP_000145163.1 sterile alpha motif-like domain-containing protein -
DXE39_RS15040 2894096..2894356 + 261 WP_001059690.1 hypothetical protein Antitoxin
DXE39_RS15045 2894384..2894572 + 189 WP_000052076.1 hypothetical protein Toxin
DXE39_RS15050 2894760..2895329 + 570 WP_001106655.1 hypothetical protein -
DXE39_RS15055 2895417..2895701 + 285 WP_001004403.1 hypothetical protein -
DXE39_RS15060 2895762..2895980 + 219 WP_000005881.1 hypothetical protein -
DXE39_RS15065 2896478..2896678 - 201 WP_001059082.1 cold-shock protein -
DXE39_RS15070 2897035..2897722 - 688 Protein_2796 thermonuclease family protein -
DXE39_RS15075 2898063..2898545 - 483 WP_000824489.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2891179..2897722 6543


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 63 a.a.        Molecular weight: 7142.82 Da        Isoelectric Point: 9.9971

>T294083 WP_000052076.1 NZ_LT992460:2894384-2894572 [Staphylococcus aureus]
MSLHFAILFWLALIFLVAATFILVLMKKTGKESKKESYLSFTVILYIFGFAILIYTFIFGVL

Download         Length: 189 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9940.09 Da        Isoelectric Point: 4.0624

>AT294083 WP_001059690.1 NZ_LT992460:2894096-2894356 [Staphylococcus aureus]
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0E0VP18

Antitoxin

Source ID Structure
AlphaFold DB A0A0E0VN56

References