Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | TscAT/- |
Location | 2560586..2561115 | Replicon | chromosome |
Accession | NZ_LT992436 | ||
Organism | Staphylococcus aureus isolate 1549-REV |
Toxin (Protein)
Gene name | TscT | Uniprot ID | K7ZRX6 |
Locus tag | DYY98_RS13110 | Protein ID | WP_001103939.1 |
Coordinates | 2560798..2561115 (+) | Length | 106 a.a. |
Antitoxin (Protein)
Gene name | TscA | Uniprot ID | X5IY59 |
Locus tag | DYY98_RS13105 | Protein ID | WP_001058494.1 |
Coordinates | 2560586..2560795 (+) | Length | 70 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
DYY98_RS13070 | 2556916..2557380 | + | 465 | WP_001085185.1 | SsrA-binding protein SmpB | - |
DYY98_RS13080 | 2557943..2559049 | - | 1107 | WP_000149511.1 | site-specific integrase | - |
DYY98_RS13085 | 2559039..2559842 | - | 804 | WP_000358990.1 | helix-turn-helix domain-containing protein | - |
DYY98_RS13090 | 2559978..2560181 | + | 204 | WP_001045296.1 | transcriptional regulator | - |
DYY98_RS13095 | 2560217..2560435 | + | 219 | WP_000163544.1 | helix-turn-helix domain-containing protein | - |
DYY98_RS13100 | 2560447..2560593 | + | 147 | WP_000784885.1 | hypothetical protein | - |
DYY98_RS13105 | 2560586..2560795 | + | 210 | WP_001058494.1 | hypothetical protein | Antitoxin |
DYY98_RS13110 | 2560798..2561115 | + | 318 | WP_001103939.1 | DUF1474 family protein | Toxin |
DYY98_RS13115 | 2561179..2562048 | + | 870 | WP_001002717.1 | primase alpha helix C-terminal domain-containing protein | - |
DYY98_RS13120 | 2562065..2562589 | + | 525 | WP_111125118.1 | hypothetical protein | - |
DYY98_RS13125 | 2562601..2563730 | + | 1130 | WP_115657120.1 | IS3 family transposase | - |
DYY98_RS13130 | 2563747..2564748 | + | 1002 | Protein_2439 | virulence-associated protein E | - |
DYY98_RS13135 | 2565049..2565411 | + | 363 | WP_001039170.1 | hypothetical protein | - |
DYY98_RS13140 | 2565413..2565697 | + | 285 | WP_000998185.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | sec / sell / vWbp | 2557943..2600707 | 42764 | |
- | flank | IS/Tn | - | - | 2562601..2562882 | 281 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 106 a.a. Molecular weight: 12547.17 Da Isoelectric Point: 5.0161
>T294030 WP_001103939.1 NZ_LT992436:2560798-2561115 [Staphylococcus aureus]
MNWEIKDLMCDIEVIKQKINDVATKHAWFVEDRFVKNELETKREHINFSASYLEHRIQNEHTVELLHVYLKEFGELIQKF
HEIEKASSENFGEVSDDAQKLKITE
MNWEIKDLMCDIEVIKQKINDVATKHAWFVEDRFVKNELETKREHINFSASYLEHRIQNEHTVELLHVYLKEFGELIQKF
HEIEKASSENFGEVSDDAQKLKITE
Download Length: 318 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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