Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4757122..4757267 Replicon chromosome
Accession NZ_LT991957
Organism Enterobacter cloacae complex sp. isolate C45

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4757129..4757232 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4757122..4757267 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DBR02_RS23350 4752149..4752646 + 498 WP_058652700.1 single-stranded DNA-binding protein SSB1 -
DBR02_RS23355 4752672..4752893 + 222 WP_058689413.1 hypothetical protein -
DBR02_RS23360 4752893..4753045 + 153 WP_058689414.1 DUF1317 family protein -
DBR02_RS23365 4753042..4753707 + 666 WP_107535592.1 DNA methyltransferase -
DBR02_RS23370 4753707..4753931 + 225 WP_058689424.1 hypothetical protein -
DBR02_RS23380 4754247..4754516 + 270 WP_107535593.1 hypothetical protein -
DBR02_RS23385 4754519..4754737 + 219 WP_107535594.1 TraR/DksA family transcriptional regulator -
DBR02_RS23390 4754737..4755129 + 393 WP_107535595.1 DUF2591 family protein -
DBR02_RS23395 4755107..4755346 + 240 WP_058689421.1 DUF4222 domain-containing protein -
DBR02_RS23400 4755356..4755565 + 210 WP_058689420.1 hypothetical protein -
DBR02_RS23405 4755725..4755997 + 273 WP_023300430.1 hypothetical protein -
DBR02_RS23410 4755966..4757051 + 1086 WP_063158908.1 phage integrase Arm DNA-binding domain-containing protein -
- 4757122..4757267 + 146 - - Antitoxin
- 4757129..4757232 - 104 - - Toxin
DBR02_RS23415 4757373..4757711 - 339 WP_063868473.1 YebY family protein -
DBR02_RS23420 4757728..4758597 - 870 WP_107535596.1 copper homeostasis membrane protein CopD -
DBR02_RS23425 4758599..4758970 - 372 WP_107535597.1 CopC domain-containing protein YobA -
DBR02_RS23430 4759108..4759338 + 231 WP_003859784.1 DNA polymerase III subunit theta -
DBR02_RS23435 4759450..4760100 + 651 WP_107535598.1 carbon-nitrogen hydrolase family protein -
DBR02_RS23440 4760125..4760787 + 663 WP_063450101.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T294000 NZ_LT991957:c4757232-4757129 [Enterobacter cloacae complex sp.]
GGCAAGGCGATTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT294000 NZ_LT991957:4757122-4757267 [Enterobacter cloacae complex sp.]
AATAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTCAATCGCCTTGCCCTTTAAGAATAGATGACGACGTCAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References