Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1132037..1132694 Replicon chromosome
Accession NZ_LT991957
Organism Enterobacter cloacae complex sp. isolate C45

Toxin (Protein)


Gene name cptA Uniprot ID A0A4V2LUM0
Locus tag DBR02_RS05750 Protein ID WP_063451987.1
Coordinates 1132037..1132447 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID G8LDB7
Locus tag DBR02_RS05755 Protein ID WP_003863437.1
Coordinates 1132428..1132694 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DBR02_RS05730 1128035..1129768 - 1734 WP_063867895.1 single-stranded-DNA-specific exonuclease RecJ -
DBR02_RS05735 1129774..1130487 - 714 WP_063451984.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
DBR02_RS05740 1130516..1131412 - 897 WP_063451985.1 site-specific tyrosine recombinase XerD -
DBR02_RS05745 1131514..1132035 + 522 WP_107533681.1 flavodoxin FldB -
DBR02_RS05750 1132037..1132447 - 411 WP_063451987.1 protein YgfX Toxin
DBR02_RS05755 1132428..1132694 - 267 WP_003863437.1 FAD assembly factor SdhE Antitoxin
DBR02_RS05760 1132988..1133968 + 981 WP_107533682.1 tRNA-modifying protein YgfZ -
DBR02_RS05765 1134053..1134712 - 660 WP_047729440.1 hemolysin III family protein -
DBR02_RS05770 1134979..1135710 + 732 WP_107533683.1 MurR/RpiR family transcriptional regulator -
DBR02_RS05775 1135827..1137260 + 1434 WP_107533684.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16277.13 Da        Isoelectric Point: 11.4775

>T293992 WP_063451987.1 NZ_LT991957:c1132447-1132037 [Enterobacter cloacae complex sp.]
VVLWQSDLRVSWRSQWMSLLLHGLVAALVLLVPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWEMIGTPWMLNTGMMLRLRRVEDNRRQHLWLAADSMDAAEWRDLRRLIVQQPTQE

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10526.96 Da        Isoelectric Point: 4.8310

>AT293992 WP_003863437.1 NZ_LT991957:c1132694-1132428 [Enterobacter cloacae complex sp.]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
QERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4V2LUM0

Antitoxin

Source ID Structure
AlphaFold DB A0A837F8P5

References