Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3573868..3574071 Replicon chromosome
Accession NZ_LT991954
Organism Enterobacter hormaechei subsp. steigerwaltii isolate C309

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3573875..3573978 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3573868..3574071 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DBR08_RS17440 3570222..3570437 + 216 WP_063844398.1 hypothetical protein -
DBR08_RS17445 3570437..3570733 + 297 WP_063844396.1 DUF4406 domain-containing protein -
DBR08_RS17450 3570730..3570921 + 192 WP_063844395.1 DUF1382 family protein -
DBR08_RS17455 3571013..3571231 + 219 WP_063844394.1 TraR/DksA family transcriptional regulator -
DBR08_RS17460 3571231..3571743 + 513 WP_063844393.1 class I SAM-dependent methyltransferase -
DBR08_RS17465 3571706..3571945 + 240 WP_039025583.1 DUF4222 domain-containing protein -
DBR08_RS17470 3571955..3572311 + 357 WP_063844391.1 DUF551 domain-containing protein -
DBR08_RS17475 3572471..3572743 + 273 WP_023300430.1 hypothetical protein -
DBR08_RS17480 3572712..3573797 + 1086 WP_063844390.1 phage integrase Arm DNA-binding domain-containing protein -
- 3573868..3574071 + 204 - - Antitoxin
- 3573875..3573978 - 104 - - Toxin
DBR08_RS17485 3574120..3574458 - 339 WP_003859787.1 YebY family protein -
DBR08_RS17490 3574475..3575344 - 870 WP_045341273.1 copper homeostasis membrane protein CopD -
DBR08_RS17495 3575346..3575717 - 372 WP_017384342.1 CopC domain-containing protein YobA -
DBR08_RS17500 3575855..3576085 + 231 WP_003859784.1 DNA polymerase III subunit theta -
DBR08_RS17505 3576197..3576847 + 651 WP_045341276.1 carbon-nitrogen hydrolase family protein -
DBR08_RS17510 3576872..3577534 + 663 WP_039270549.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - gtrA / gtrB 3503825..3594816 90991


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T293976 NZ_LT991954:c3573978-3573875 [Enterobacter hormaechei subsp. steigerwaltii]
GGCAAGGCGATTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 204 bp

>AT293976 NZ_LT991954:3573868-3574071 [Enterobacter hormaechei subsp. steigerwaltii]
AATAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTCAATCGCCTTGCCCTTTAAGAATAGATGACGACGTCAGGTTTTCCAGTCCACAGCAAAAGTG
GTCTGAAAAAAAGCGTCAGAACATCACTAAATGTGAAAAACCGC

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References