Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 5774661..5775180 Replicon chromosome
Accession NZ_LT985192
Organism Pseudomonas syringae strain CFBP 2116

Toxin (Protein)


Gene name relE Uniprot ID Q48Q48
Locus tag DTQ61_RS27865 Protein ID WP_002551445.1
Coordinates 5774661..5774951 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID S6UWW5
Locus tag DTQ61_RS27870 Protein ID WP_002551444.1
Coordinates 5774941..5775180 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DTQ61_RS27835 5770085..5770888 - 804 WP_003417182.1 IS21-like element ISPsy20 family helper ATPase IstB -
DTQ61_RS27840 5770881..5772380 - 1500 WP_103356851.1 IS21 family transposase -
DTQ61_RS27850 5772963..5773385 + 423 WP_005746664.1 DUF1493 family protein -
DTQ61_RS27855 5773691..5774428 + 738 WP_060403416.1 hypothetical protein -
DTQ61_RS27865 5774661..5774951 - 291 WP_002551445.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DTQ61_RS27870 5774941..5775180 - 240 WP_002551444.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
DTQ61_RS27875 5775344..5775817 - 474 WP_002551443.1 GNAT family N-acetyltransferase -
DTQ61_RS27880 5775919..5776467 - 549 WP_044318253.1 GNAT family N-acetyltransferase -
DTQ61_RS27885 5776627..5777121 + 495 WP_004667254.1 hypothetical protein -
DTQ61_RS27890 5777155..5778429 - 1275 WP_004667253.1 OprD family porin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11316.19 Da        Isoelectric Point: 10.2579

>T293966 WP_002551445.1 NZ_LT985192:c5774951-5774661 [Pseudomonas syringae]
MTYNLEFDARALKEWHKLGDTVRQQLKKKLATILVAPRVEANRLHALPDCYKIKLRSSGYRLVYQVIDQEVVVFVVAVDK
REREEVYRKATDRLGR

Download         Length: 291 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8955.34 Da        Isoelectric Point: 4.6017

>AT293966 WP_002551444.1 NZ_LT985192:c5775180-5774941 [Pseudomonas syringae]
MASINVRIDDDLKARAYLELEKLGVTPSELLRQTLQYVAERGQLPFKTVLMTEEDEALLATVRERLAAPQRVKVSLDDL

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2G4DBS4

Antitoxin

Source ID Structure
AlphaFold DB A0A0K8M1G9

References