Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 156744..157324 Replicon chromosome
Accession NZ_LT985192
Organism Pseudomonas syringae strain CFBP 2116

Toxin (Protein)


Gene name PumA Uniprot ID A0A2G4CV40
Locus tag DTQ61_RS00815 Protein ID WP_044322659.1
Coordinates 157025..157324 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID A0A2G4CUT8
Locus tag DTQ61_RS00810 Protein ID WP_003407168.1
Coordinates 156744..157028 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DTQ61_RS00790 152018..153052 + 1035 WP_057427112.1 IS110 family transposase -
DTQ61_RS00795 153509..154527 - 1019 Protein_139 tyrosine protein phosphatase -
DTQ61_RS00800 154953..155987 + 1035 WP_057427112.1 IS110 family transposase -
DTQ61_RS00805 156361..156669 + 309 WP_180275929.1 DUF4113 domain-containing protein -
DTQ61_RS00810 156744..157028 - 285 WP_003407168.1 putative addiction module antidote protein Antitoxin
DTQ61_RS00815 157025..157324 - 300 WP_044322659.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DTQ61_RS00825 157926..158342 + 417 WP_060403106.1 hypothetical protein -
DTQ61_RS00835 158738..159391 + 654 WP_060403115.1 AAA family ATPase -
DTQ61_RS00840 159480..159731 + 252 WP_003348789.1 ribbon-helix-helix protein, CopG family -
DTQ61_RS00845 159996..160637 + 642 WP_060403107.1 SOS response-associated peptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 111390..159731 48341


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-95)

Antitoxin

Uncharacterized protein HI1420

(10-92)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11170.80 Da        Isoelectric Point: 9.9231

>T293965 WP_044322659.1 NZ_LT985192:c157324-157025 [Pseudomonas syringae]
MTTIKQTSTYMAWERRLKDQKAKAAIAARIFRVANGLMGDVSPVGQGVSELRIHVGPGYRVYFQQRGDELILLLCGGDKS
SQSRDIETAKKLADQWWQE

Download         Length: 300 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10277.83 Da        Isoelectric Point: 5.0916

>AT293965 WP_003407168.1 NZ_LT985192:c157028-156744 [Pseudomonas syringae]
MKEQIFDYDPAAALDGPEAIAIFISDAFETGDAEYIAKAMGVVARAKGMTELARETGLSREQLYRSFSSKGNPTLKTMLT
VMRALGVDMTARMH

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2G4CV40

Antitoxin

Source ID Structure
AlphaFold DB A0A2G4CUT8

References