Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 2772789..2773341 Replicon chromosome
Accession NZ_LT985188
Organism Micropruina glycogenica isolate

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag MPLG2_RS13005 Protein ID WP_105186500.1
Coordinates 2772789..2773106 (-) Length 106 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag MPLG2_RS13010 Protein ID WP_105187664.1
Coordinates 2773108..2773341 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MPLG2_RS12980 2768115..2769584 - 1470 WP_105186496.1 DNA-3-methyladenine glycosylase 2 family protein -
MPLG2_RS12985 2769758..2770678 - 921 WP_105186497.1 phosphotransferase -
MPLG2_RS19060 2771076..2771297 + 222 WP_197709940.1 hypothetical protein -
MPLG2_RS12995 2771365..2771913 - 549 WP_105186498.1 DUF1905 domain-containing protein -
MPLG2_RS13000 2771967..2772467 + 501 WP_105186499.1 DinB family protein -
MPLG2_RS13005 2772789..2773106 - 318 WP_105186500.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
MPLG2_RS13010 2773108..2773341 - 234 WP_105187664.1 ribbon-helix-helix domain-containing protein Antitoxin
MPLG2_RS13020 2773577..2776048 - 2472 WP_105186501.1 ATP-dependent DNA ligase -
MPLG2_RS13025 2776095..2776553 + 459 WP_105187665.1 YdeI/OmpD-associated family protein -
MPLG2_RS13030 2777124..2777957 + 834 WP_105186502.1 CPBP family intramembrane metalloprotease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(10-92)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 106 a.a.        Molecular weight: 11188.09 Da        Isoelectric Point: 4.7247

>T293962 WP_105186500.1 NZ_LT985188:c2773106-2772789 [Micropruina glycogenica]
VREICLARLDKTRPVVVLTREAARAAMTKVTVAPITSTIKGLNSEVSVGPDNGLEQLSVISLDNVVTIPANLLGRTVGFL
SSEQEMLLAKAIVLAYDLDIALLDT

Download         Length: 318 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8257.36 Da        Isoelectric Point: 4.3138

>AT293962 WP_105187664.1 NZ_LT985188:c2773341-2773108 [Micropruina glycogenica]
MSTQIAVRLPDEMVAFLDQAVAQGKAASRAQLVSAALEREMRRQAAEADAVILRQQGAADDLDPLVEWTVGHLDIAG

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References