Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 971278..971831 Replicon chromosome
Accession NZ_LT985188
Organism Micropruina glycogenica isolate

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MPLG2_RS04550 Protein ID WP_105185117.1
Coordinates 971559..971831 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MPLG2_RS04545 Protein ID WP_173909596.1
Coordinates 971278..971553 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MPLG2_RS04520 966394..966984 - 591 WP_105185113.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
MPLG2_RS04525 967176..968840 + 1665 WP_197710085.1 Eco57I restriction-modification methylase domain-containing protein -
MPLG2_RS04530 968885..969622 + 738 WP_105185115.1 type II restriction endonuclease -
MPLG2_RS04535 969675..970268 - 594 WP_105185116.1 hypothetical protein -
MPLG2_RS04540 970261..971115 - 855 WP_197710086.1 HAD family hydrolase -
MPLG2_RS04545 971278..971553 + 276 WP_173909596.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
MPLG2_RS04550 971559..971831 + 273 WP_105185117.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MPLG2_RS04555 971833..972717 - 885 WP_158680874.1 alpha/beta hydrolase -
MPLG2_RS04560 973087..973824 + 738 WP_158680875.1 relaxase domain-containing protein -
MPLG2_RS04565 973915..975633 + 1719 WP_105185120.1 AAA family ATPase -
MPLG2_RS18305 976549..976815 + 267 WP_158680876.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 932844..982477 49633


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10357.08 Da        Isoelectric Point: 10.9613

>T293960 WP_105185117.1 NZ_LT985188:971559-971831 [Micropruina glycogenica]
VPGPYEVVFTRTARRALERDLPEKVAAAAFEFIMGALRANPRRVGKPLREPLAPLYAARRGEYRVIYRIVDQRLVIEIVS
VVHRRDAYHS

Download         Length: 273 bp

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 9674.68 Da        Isoelectric Point: 4.0746

>AT293960 WP_173909596.1 NZ_LT985188:971278-971553 [Micropruina glycogenica]
MTTLSLAEARANLSKLVESAVSTHERFEVTRNGDRVAVLLGADDYDSLLETLDILSSPDEVEAIRAGLDDLESGEVSSAD
EVRAALAARGK

Download         Length: 276 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References