Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 971278..971831 Replicon chromosome
Accession NZ_LT985188
Organism Micropruina glycogenica isolate

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MPLG2_RS04550 Protein ID WP_105185117.1
Coordinates 971559..971831 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MPLG2_RS04545 Protein ID WP_173909596.1
Coordinates 971278..971553 (+) Length 92 a.a.

Genomic Context


MPLG2_RS04525MPLG2_RS04530MPLG2_RS04545MPLG2_RS04550MPLG2_RS04560MPLG2_RS04565MPLG2_RS18305MPLG2_RS04520MPLG2_RS04535MPLG2_RS04540MPLG2_RS04555
Location: 967176..968840 (1665 bp)
Type: Others
Protein ID: WP_197710085.1
Location: 968885..969622 (738 bp)
Type: Others
Protein ID: WP_105185115.1
Location: 971278..971553 (276 bp)
Type: Antitoxin
Protein ID: WP_173909596.1
Location: 971559..971831 (273 bp)
Type: Toxin
Protein ID: WP_105185117.1
Location: 973087..973824 (738 bp)
Type: Others
Protein ID: WP_158680875.1
Location: 973915..975633 (1719 bp)
Type: Others
Protein ID: WP_105185120.1
Location: 976549..976815 (267 bp)
Type: Others
Protein ID: WP_158680876.1
Location: 966394..966984 (591 bp)
Type: Others
Protein ID: WP_105185113.1
Location: 969675..970268 (594 bp)
Type: Others
Protein ID: WP_105185116.1
Location: 970261..971115 (855 bp)
Type: Others
Protein ID: WP_197710086.1
Location: 971833..972717 (885 bp)
Type: Others
Protein ID: WP_158680874.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
MPLG2_RS04520966394..966984-591WP_105185113.1type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein-
MPLG2_RS04525967176..968840+1665WP_197710085.1Eco57I restriction-modification methylase domain-containing protein-
MPLG2_RS04530968885..969622+738WP_105185115.1type II restriction endonuclease-
MPLG2_RS04535969675..970268-594WP_105185116.1hypothetical protein-
MPLG2_RS04540970261..971115-855WP_197710086.1HAD family hydrolase-
MPLG2_RS04545971278..971553+276WP_173909596.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
MPLG2_RS04550971559..971831+273WP_105185117.1type II toxin-antitoxin system RelE/ParE family toxinToxin
MPLG2_RS04555971833..972717-885WP_158680874.1alpha/beta hydrolase-
MPLG2_RS04560973087..973824+738WP_158680875.1relaxase domain-containing protein-
MPLG2_RS04565973915..975633+1719WP_105185120.1AAA family ATPase-
MPLG2_RS18305976549..976815+267WP_158680876.1hypothetical protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideIntegrative and Conjugative Element--932844..98247749633


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 91 a.a.        Molecular weight: 10357.08 Da        Isoelectric Point: 10.9613

>T293960 WP_105185117.1 NZ_LT985188:971559-971831 [Micropruina glycogenica]
VPGPYEVVFTRTARRALERDLPEKVAAAAFEFIMGALRANPRRVGKPLREPLAPLYAARRGEYRVIYRIVDQRLVIEIVS
VVHRRDAYHS

Download         Length: 273 bp


Antitoxin


Download         Length: 92 a.a.        Molecular weight: 9674.68 Da        Isoelectric Point: 4.0746

>AT293960 WP_173909596.1 NZ_LT985188:971278-971553 [Micropruina glycogenica]
MTTLSLAEARANLSKLVESAVSTHERFEVTRNGDRVAVLLGADDYDSLLETLDILSSPDEVEAIRAGLDDLESGEVSSAD
EVRAALAARGK

Download         Length: 276 bp


Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References