Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 937468..937999 Replicon chromosome
Accession NZ_LT984798
Organism Desulfovibrio sp. G11 isolate G11PacBio

Toxin (Protein)


Gene name relE Uniprot ID A0A807ZMP4
Locus tag DSVG11_RS04115 Protein ID WP_072311512.1
Coordinates 937468..937764 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7W8FFT7
Locus tag DSVG11_RS04120 Protein ID WP_072311511.1
Coordinates 937754..937999 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DSVG11_RS04095 932862..933029 - 168 WP_096152722.1 hypothetical protein -
DSVG11_RS04100 933286..934914 - 1629 WP_072311513.1 VWA domain-containing protein -
DSVG11_RS04105 934919..935956 - 1038 WP_096152721.1 DUF3150 domain-containing protein -
DSVG11_RS04110 935966..937318 - 1353 WP_072311531.1 AAA family ATPase -
DSVG11_RS04115 937468..937764 - 297 WP_072311512.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DSVG11_RS04120 937754..937999 - 246 WP_072311511.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
DSVG11_RS04125 938128..939291 - 1164 WP_072311510.1 hypothetical protein -
DSVG11_RS04130 939360..940061 - 702 WP_072311509.1 ERF family protein -
DSVG11_RS04135 940232..940492 - 261 WP_072311508.1 Txe/YoeB family addiction module toxin -
DSVG11_RS04140 940473..940745 - 273 WP_072311507.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
DSVG11_RS04145 940857..941720 - 864 WP_096152720.1 restriction endonuclease -
DSVG11_RS04150 941735..942688 - 954 WP_143142576.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 932862..945194 12332


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-64)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11615.64 Da        Isoelectric Point: 10.2579

>T293957 WP_072311512.1 NZ_LT984798:c937764-937468 [Desulfovibrio sp. G11]
MSYSLQFHEIALKEWRKLDASIREQFKKKLAERLEHPRVPSSALSGMRDCYKIKLRSIGYRLVYMVDDGILFVTVISIGK
RERLEVYRKALQRVTPEE

Download         Length: 297 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9050.34 Da        Isoelectric Point: 4.8081

>AT293957 WP_072311511.1 NZ_LT984798:c937999-937754 [Desulfovibrio sp. G11]
MDPIHANITVSVTELKRNFANILATAKDAPVAVLNHNKPEAYLLSAKHYEEILGILEDLEDKKIVESREHGPFVTVTLDE
L

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A807ZMP4

Antitoxin

Source ID Structure
AlphaFold DB A0A7W8FFT7

References