Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /Xre(antitoxin) |
Location | 4827435..4828693 | Replicon | chromosome |
Accession | NZ_LT969520 | ||
Organism | Pseudomonas aeruginosa isolate RW109 |
Toxin (Protein)
Gene name | - | Uniprot ID | V6AJ34 |
Locus tag | RW109_RS26535 | Protein ID | WP_003086331.1 |
Coordinates | 4827435..4828190 (-) | Length | 252 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | V6AJU7 |
Locus tag | RW109_RS26540 | Protein ID | WP_003086329.1 |
Coordinates | 4828325..4828693 (-) | Length | 123 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
RW109_RS26525 | 4822606..4825149 | + | 2544 | WP_033955245.1 | acyl-homoserine-lactone acylase QuiP | - |
RW109_RS26530 | 4825305..4826666 | - | 1362 | WP_003120632.1 | DNA recombination protein RmuC | - |
RW109_RS26535 | 4827435..4828190 | - | 756 | WP_003086331.1 | RES family NAD+ phosphorylase | Toxin |
RW109_RS26540 | 4828325..4828693 | - | 369 | WP_003086329.1 | DUF2384 domain-containing protein | Antitoxin |
RW109_RS26545 | 4828766..4830052 | - | 1287 | WP_003086327.1 | FAD-binding oxidoreductase | - |
RW109_RS26550 | 4830108..4831697 | - | 1590 | WP_023464367.1 | aldehyde dehydrogenase family protein | - |
RW109_RS26555 | 4831776..4832252 | + | 477 | WP_004353334.1 | elongation factor GreAB | - |
RW109_RS38635 | 4832255..4832530 | - | 276 | WP_023088486.1 | zinc ribbon domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 252 a.a. Molecular weight: 28236.34 Da Isoelectric Point: 7.7294
>T293948 WP_003086331.1 NZ_LT969520:c4828190-4827435 [Pseudomonas aeruginosa]
VSEIWRQCKGERHVRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
VSEIWRQCKGERHVRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
Download Length: 756 bp
Antitoxin
Download Length: 123 a.a. Molecular weight: 13367.63 Da Isoelectric Point: 9.9874
>AT293948 WP_003086329.1 NZ_LT969520:c4828693-4828325 [Pseudomonas aeruginosa]
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
Download Length: 369 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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