293932

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RHH
Location 70235..70782 Replicon plasmid PP1
Accession NZ_LT963410
Organism Pseudomonas syringae isolate CFBP3840

Toxin (Protein)


Gene name relE Uniprot ID H1ZWV0
Locus tag C6H39_RS29190 Protein ID WP_015060661.1
Coordinates 70507..70782 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID H1ZWV1
Locus tag C6H39_RS29185 Protein ID WP_015060662.1
Coordinates 70235..70507 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6H39_RS29140 65834..66463 + 630 WP_024421519.1 AAA family ATPase -
C6H39_RS29145 66460..66690 + 231 WP_019742104.1 hypothetical protein -
C6H39_RS29150 66744..67253 - 510 WP_019742103.1 GNAT family N-acetyltransferase -
C6H39_RS29155 67250..67531 - 282 WP_019742102.1 DUF1778 domain-containing protein -
C6H39_RS29165 67815..68493 + 679 Protein_79 recombinase family protein -
C6H39_RS29170 68493..68684 + 192 WP_010208571.1 hypothetical protein -
C6H39_RS32120 68867..69040 + 174 WP_005759896.1 hypothetical protein -
C6H39_RS29175 69040..69645 + 606 WP_044311023.1 hypothetical protein -
C6H39_RS29180 69721..69999 - 279 Protein_83 hypothetical protein -
C6H39_RS29185 70235..70507 + 273 WP_015060662.1 ribbon-helix-helix domain-containing protein Antitoxin
C6H39_RS29190 70507..70782 + 276 WP_015060661.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C6H39_RS29195 70868..71338 - 471 Protein_86 transposase zinc-binding domain-containing protein -
C6H39_RS29205 71719..73749 - 2031 WP_031598378.1 methyl-accepting chemotaxis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..110420 110420


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-47)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10751.33 Da        Isoelectric Point: 7.0126

>T293932 WP_015060661.1 NZ_LT963410:70507-70782 [Pseudomonas syringae]
MELKWTSKALSDITRLYEFLALANQPAAARVVQQLTTAPTTLLTNPRIGERLEEFEPKDVRRIQIGQYEMRYEIADSTIY
LLRLWHTREDR

Download         Length: 276 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10076.40 Da        Isoelectric Point: 5.6994

>AT293932 WP_015060662.1 NZ_LT963410:70235-70507 [Pseudomonas syringae]
MATTAKTRSVTAHVPVQLAEKVDLMAERLERSKNWIVKQALSAWIDQEEERSRLTREALADVDAGRVIDHQAVQAWADSL
STDTPLPVPR

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A554FV80

Antitoxin

Source ID Structure
AlphaFold DB A0A3M4CJB9

References