Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 250324..250843 Replicon chromosome
Accession NZ_LT963409
Organism Pseudomonas syringae isolate CFBP3840

Toxin (Protein)


Gene name relE Uniprot ID Q48Q48
Locus tag C6H39_RS01170 Protein ID WP_002551445.1
Coordinates 250553..250843 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID S6UWW5
Locus tag C6H39_RS01165 Protein ID WP_002551444.1
Coordinates 250324..250563 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6H39_RS01145 247075..248349 + 1275 WP_004667253.1 OprD family porin -
C6H39_RS01150 248383..248877 - 495 WP_004667254.1 hypothetical protein -
C6H39_RS01155 249037..249585 + 549 WP_044318253.1 GNAT family N-acetyltransferase -
C6H39_RS01160 249687..250160 + 474 WP_002551443.1 GNAT family N-acetyltransferase -
C6H39_RS01165 250324..250563 + 240 WP_002551444.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
C6H39_RS01170 250553..250843 + 291 WP_002551445.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C6H39_RS01180 251076..251813 - 738 WP_060403416.1 hypothetical protein -
C6H39_RS01185 252119..252541 - 423 WP_005746664.1 DUF1493 family protein -
C6H39_RS01195 253124..254623 + 1500 WP_103356851.1 IS21 family transposase -
C6H39_RS01200 254616..255419 + 804 WP_003417182.1 IS21-like element ISPsy20 family helper ATPase IstB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11316.19 Da        Isoelectric Point: 10.2579

>T293929 WP_002551445.1 NZ_LT963409:250553-250843 [Pseudomonas syringae]
MTYNLEFDARALKEWHKLGDTVRQQLKKKLATILVAPRVEANRLHALPDCYKIKLRSSGYRLVYQVIDQEVVVFVVAVDK
REREEVYRKATDRLGR

Download         Length: 291 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8955.34 Da        Isoelectric Point: 4.6017

>AT293929 WP_002551444.1 NZ_LT963409:250324-250563 [Pseudomonas syringae]
MASINVRIDDDLKARAYLELEKLGVTPSELLRQTLQYVAERGQLPFKTVLMTEEDEALLATVRERLAAPQRVKVSLDDL

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2G4DBS4

Antitoxin

Source ID Structure
AlphaFold DB A0A0K8M1G9

References