Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1096953..1097494 Replicon chromosome
Accession NZ_LT963408
Organism Pseudomonas syringae group genomosp. 3 isolate CFBP6411

Toxin (Protein)


Gene name relE Uniprot ID A0A2K4W910
Locus tag C6H37_RS05615 Protein ID WP_060402130.1
Coordinates 1096953..1097228 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2S4IDD5
Locus tag C6H37_RS05620 Protein ID WP_005736615.1
Coordinates 1097228..1097494 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6H37_RS05585 1092083..1093108 - 1026 WP_104698281.1 TRAP transporter substrate-binding protein -
C6H37_RS05590 1093166..1094050 - 885 WP_005736620.1 SMP-30/gluconolactonase/LRE family protein -
C6H37_RS05595 1094107..1094934 - 828 WP_005736619.1 NAD(P)-dependent oxidoreductase -
C6H37_RS05600 1095113..1096381 - 1269 WP_017698468.1 OprD family porin -
C6H37_RS05615 1096953..1097228 - 276 WP_060402130.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C6H37_RS05620 1097228..1097494 - 267 WP_005736615.1 ribbon-helix-helix domain-containing protein Antitoxin
C6H37_RS05625 1097659..1099581 - 1923 WP_017700186.1 methyl-accepting chemotaxis protein -
C6H37_RS05630 1099940..1101820 + 1881 WP_005736612.1 methyl-accepting chemotaxis protein -
C6H37_RS05635 1101949..1102212 - 264 WP_005736610.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(8-45)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10683.37 Da        Isoelectric Point: 7.0121

>T293926 WP_060402130.1 NZ_LT963408:c1097228-1096953 [Pseudomonas syringae group genomosp. 3]
MELMWTSKALSDVARLYDFLAVASQPAAAQTVQKLTAAPIMLLSNPRIGERLEEFEPRDVRKIQIGRYEMRYEIVDSTIY
LLRLWHTREDR

Download         Length: 276 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9915.20 Da        Isoelectric Point: 5.6158

>AT293926 WP_005736615.1 NZ_LT963408:c1097494-1097228 [Pseudomonas syringae group genomosp. 3]
MTTKTRSVTAHIPEQLAEKVDLMAERLERSKNWIVKQALSAWIDQEEERSRLTREALADVDAGHVIDHQAVQAWADSLST
ATPLPVPR

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2K4W910

Antitoxin

Source ID Structure
AlphaFold DB A0A2S4IDD5

References