Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2552..3225 Replicon plasmid PP5
Accession NZ_LT963407
Organism Pseudomonas syringae pv. avii isolate CFBP3846

Toxin (Protein)


Gene name vapC Uniprot ID A0A2K4W4Y6
Locus tag C6H38_RS31600 Protein ID WP_060412717.1
Coordinates 2552..2971 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag C6H38_RS31605 Protein ID WP_060412719.1
Coordinates 2968..3225 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6H38_RS31590 686..1621 - 936 WP_060412716.1 syringolide biosynthetic protein AvrD1 -
C6H38_RS31595 1896..2511 - 616 Protein_2 recombinase family protein -
C6H38_RS31600 2552..2971 - 420 WP_060412717.1 type II toxin-antitoxin system VapC family toxin Toxin
C6H38_RS31605 2968..3225 - 258 WP_060412719.1 Arc family DNA-binding protein Antitoxin
C6H38_RS31610 3593..4225 + 633 WP_003381804.1 ParA family protein -
C6H38_RS31615 4261..4515 + 255 WP_003381801.1 hypothetical protein -
C6H38_RS31620 4939..5604 - 666 WP_060412718.1 LexA family transcriptional regulator -
C6H38_RS31625 5692..5922 + 231 WP_010215521.1 helix-turn-helix domain-containing protein -
C6H38_RS31630 6273..6980 + 708 WP_103724609.1 lytic transglycosylase domain-containing protein -
C6H38_RS31635 6980..7315 + 336 WP_103724610.1 conjugal transfer protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..41285 41285


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin

Arc-like DNA binding domain

(9-46)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15168.46 Da        Isoelectric Point: 4.7010

>T293922 WP_060412717.1 NZ_LT963407:c2971-2552 [Pseudomonas syringae pv. avii]
MILLDTNVISEPQRREPNAHVLDWIDAQALETLYLSTITVAELRAGIALMPVGKRQDSLRENLEKHLLPMFANRVLSFDM
TCTKTYAELLAKSRAAGLAVETADAFIAAIALANGFTVATRDTGPFEAAGLNVINPWEA

Download         Length: 420 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9374.60 Da        Isoelectric Point: 9.0330

>AT293922 WP_060412719.1 NZ_LT963407:c3225-2968 [Pseudomonas syringae pv. avii]
VANVSVRNLPDEVHRAIRIQAALHGRSTEAEIRDILERAARPEGRVKLGSFLASIAREVGGLTDKEHTLFENTRITSPAR
AVSFE

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2K4W4Y6

Antitoxin

Source ID Structure

References