293919

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PfiT-PfiA/ParE-Phd
Location 70691..71302 Replicon plasmid PP3
Accession NZ_LT963405
Organism Pseudomonas syringae pv. avii isolate CFBP3846

Toxin (Protein)


Gene name PfiT Uniprot ID A0A3M3YY90
Locus tag C6H38_RS30770 Protein ID WP_058398778.1
Coordinates 70952..71302 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name PfiA Uniprot ID I3W0K1
Locus tag C6H38_RS30765 Protein ID WP_005618754.1
Coordinates 70691..70939 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6H38_RS30740 65933..66829 + 897 WP_003317531.1 LysR family transcriptional regulator -
C6H38_RS30745 66987..67979 + 993 WP_003317529.1 YncE family protein -
C6H38_RS30750 68309..68689 + 381 WP_003317528.1 hypothetical protein -
C6H38_RS30760 69404..70366 - 963 WP_060413825.1 tyrosine-type recombinase/integrase -
C6H38_RS30765 70691..70939 + 249 WP_005618754.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
C6H38_RS30770 70952..71302 + 351 WP_058398778.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C6H38_RS30775 71433..72206 - 774 WP_058398777.1 helix-turn-helix transcriptional regulator -
C6H38_RS30780 72315..72716 + 402 Protein_78 polyamine ABC transporter substrate-binding protein -
C6H38_RS30785 72765..73574 - 810 WP_005741073.1 IS21-like element ISPsy4 family helper ATPase IstB -
C6H38_RS30790 73571..74593 - 1023 WP_002551322.1 IS21-like element ISPsy4 family transposase -
C6H38_RS30795 74746..74940 - 195 WP_054086142.1 hypothetical protein -
C6H38_RS30800 74937..75227 - 291 WP_046835519.1 hypothetical protein -
C6H38_RS30805 75301..75666 - 366 WP_054999222.1 hypothetical protein -
C6H38_RS30810 75651..76043 - 393 WP_060414197.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..108842 108842


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-101)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12978.87 Da        Isoelectric Point: 4.1953

>T293919 WP_058398778.1 NZ_LT963405:70952-71302 [Pseudomonas syringae pv. avii]
MNTFALRFTDVAQQSLEDQVEHLAVTQGLSSAAQRIDILIDAIQDKLLSTPLGYPVSPQLSELGVLHYRELNTDGYRIFY
EVMQSVDIDEIVISLVLGGKQSVEQALIRYCLLQPI

Download         Length: 351 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9345.71 Da        Isoelectric Point: 9.8452

>AT293919 WP_005618754.1 NZ_LT963405:70691-70939 [Pseudomonas syringae pv. avii]
MRVETISYLKRNAADLPLDEPLVVTQNGVPAYVVESYADRKRRDESIALVKLLAISSREYAQGKHCSTDELKARLSRRFA
HK

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3M3YY90

Antitoxin

Source ID Structure
AlphaFold DB A0A3M3Z0L4

References