Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 3485..4152 Replicon plasmid PP1
Accession NZ_LT963403
Organism Pseudomonas syringae pv. avii isolate CFBP3846

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag C6H38_RS29365 Protein ID WP_004642352.1
Coordinates 3736..4152 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A3M5U3K4
Locus tag C6H38_RS29360 Protein ID WP_024421297.1
Coordinates 3485..3739 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6H38_RS29340 33..842 - 810 WP_005741073.1 IS21-like element ISPsy4 family helper ATPase IstB -
C6H38_RS29345 839..1861 - 1023 WP_002551322.1 IS21-like element ISPsy4 family transposase -
C6H38_RS29350 1905..2240 - 336 WP_103388890.1 hypothetical protein -
C6H38_RS29355 2278..3138 - 861 WP_057415931.1 MurR/RpiR family transcriptional regulator -
C6H38_RS29360 3485..3739 + 255 WP_024421297.1 plasmid stabilization protein Antitoxin
C6H38_RS29365 3736..4152 + 417 WP_004642352.1 type II toxin-antitoxin system VapC family toxin Toxin
C6H38_RS29370 4414..6369 - 1956 WP_104698131.1 relaxase/mobilization nuclease domain-containing protein -
C6H38_RS29375 6380..6709 - 330 WP_003344297.1 ribbon-helix-helix protein, CopG family -
C6H38_RS29380 6969..7313 + 345 WP_031599149.1 hypothetical protein -
C6H38_RS29390 7611..7889 + 279 WP_004661031.1 mobilization protein -
C6H38_RS29395 7956..8156 - 201 WP_004666908.1 hypothetical protein -
C6H38_RS29400 8224..8676 - 453 Protein_11 DUF932 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..43975 43975


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-123)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14797.07 Da        Isoelectric Point: 4.8361

>T293915 WP_004642352.1 NZ_LT963403:3736-4152 [Pseudomonas syringae pv. avii]
MIVLDTNVVSEAMKPESHLAVRAWLNDQAAETLYLSSVTLAELLFGIGALPAGKRKDMLAQALDGLMGLFRDRVLPFDID
AARRYADLAVTAKTCGRGFPTPDGYIAAIAASRGFIVASRDTAPYEAVGVSVINPWEV

Download         Length: 417 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9441.89 Da        Isoelectric Point: 10.2880

>AT293915 WP_024421297.1 NZ_LT963403:3485-3739 [Pseudomonas syringae pv. avii]
MAMLTVRNLPDDVHRALRVRAAQHGHSTEAEVREILAIAVKPETRVRLGEALAALGRKIGLTNEDFEVFNQVRDKTPAKP
LRFE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A3M5U3K4

References