Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PfiT-PfiA/ParE(toxin)
Location 5621390..5622001 Replicon chromosome
Accession NZ_LT963402
Organism Pseudomonas syringae pv. avii isolate CFBP3846

Toxin (Protein)


Gene name PfiT Uniprot ID Q4ZME8
Locus tag C6H38_RS26870 Protein ID WP_003304103.1
Coordinates 5621651..5622001 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name PfiA Uniprot ID Q4ZME7
Locus tag C6H38_RS26865 Protein ID WP_002556076.1
Coordinates 5621390..5621638 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6H38_RS26850 5616645..5617031 - 387 Protein_4975 NYN domain-containing protein -
C6H38_RS26855 5617378..5619948 - 2571 WP_060413963.1 AAA family ATPase -
C6H38_RS26860 5620093..5621055 - 963 WP_060413964.1 tyrosine-type recombinase/integrase -
C6H38_RS26865 5621390..5621638 + 249 WP_002556076.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
C6H38_RS26870 5621651..5622001 + 351 WP_003304103.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C6H38_RS26880 5622653..5624038 - 1386 WP_060413965.1 P-type conjugative transfer protein TrbL -
C6H38_RS26885 5624242..5624691 - 450 Protein_4981 conjugal transfer protein TrbJ -
C6H38_RS26895 5626361..5626669 - 309 Protein_4983 conjugal transfer protein TrbJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 5617378..5628507 11129


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-98)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12973.76 Da        Isoelectric Point: 4.7690

>T293914 WP_003304103.1 NZ_LT963402:5621651-5622001 [Pseudomonas syringae pv. avii]
MNTFALRFTDVAQQSLEDQVEHLAVHQGFSSAAQRIDTLIDAIQDKLLSTPLGYPVSHQLSELGVLHYRELNTDGYRIFY
EVRDAGDINVIVVALVLGSKQSVEQALIRYCLLQAI

Download         Length: 351 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9366.73 Da        Isoelectric Point: 9.9579

>AT293914 WP_002556076.1 NZ_LT963402:5621390-5621638 [Pseudomonas syringae pv. avii]
MRVETISFLKRNAADLPLDEPLVVTQNGVPAYVVESYADRKRRDESIALVKLLAISSREYSQGKHCSTDELKARLSRRFT
QK

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0P9GDS9

Antitoxin

Source ID Structure
AlphaFold DB A0A0P9GM89

References