293905

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PfiT-PfiA/ParE(toxin)
Location 204872..205474 Replicon chromosome
Accession NZ_LT963402
Organism Pseudomonas syringae pv. avii isolate CFBP3846

Toxin (Protein)


Gene name PfiT Uniprot ID A0A2K4T9S6
Locus tag C6H38_RS01055 Protein ID WP_060413101.1
Coordinates 205124..205474 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name PfiA Uniprot ID A0A2K4VM44
Locus tag C6H38_RS01050 Protein ID WP_060413102.1
Coordinates 204872..205111 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6H38_RS01025 199937..200380 - 444 WP_172679536.1 ATP-dependent zinc protease -
C6H38_RS01030 200430..201212 - 783 WP_024676641.1 EAL domain-containing protein -
C6H38_RS01035 201380..201787 + 408 WP_003377907.1 RNA-binding protein S4 -
C6H38_RS01040 201948..202850 + 903 WP_005613652.1 Hsp33 family molecular chaperone HslO -
C6H38_RS01045 203030..204574 + 1545 WP_060413103.1 phosphoenolpyruvate carboxykinase -
C6H38_RS01050 204872..205111 + 240 WP_060413102.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
C6H38_RS01055 205124..205474 + 351 WP_060413101.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C6H38_RS01060 205777..206229 - 453 WP_060413100.1 hypothetical protein -
C6H38_RS01065 206608..207222 - 615 WP_060413099.1 hypothetical protein -
C6H38_RS01070 207319..208026 - 708 WP_060413098.1 hypothetical protein -
C6H38_RS01075 208155..208603 - 449 Protein_202 hypothetical protein -
C6H38_RS01080 209052..209765 - 714 WP_060413097.1 cupin domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-101)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13124.08 Da        Isoelectric Point: 4.3176

>T293905 WP_060413101.1 NZ_LT963402:205124-205474 [Pseudomonas syringae pv. avii]
MNMFALRFTDVAQQSLEDQVEHLAVYQGFSPAAQRIDTLIDAIQDKLLSTPLAYPVSPQLSELGVLHYRELNADGYRIFY
EVRETDDINVIVIVLVLGGKQSVEQALIRYCLLQPI

Download         Length: 351 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9021.20 Da        Isoelectric Point: 8.9236

>AT293905 WP_060413102.1 NZ_LT963402:204872-205111 [Pseudomonas syringae pv. avii]
MRVETISYLKRNAADLPLDEPLIVTQNGVPAYVVESYADRKRRDESIALAISSREYSQGKHCSADELKARLSRRFAHKE

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2K4T9S6

Antitoxin

Source ID Structure
AlphaFold DB A0A2K4VM44

References