293901

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 21638..22085 Replicon plasmid PP4
Accession NZ_LT963399
Organism Pseudomonas cerasi isolate PL963

Toxin (Protein)


Gene name relE Uniprot ID A0A3M4C5F0
Locus tag C6H34_RS29430 Protein ID WP_003348606.1
Coordinates 21638..21910 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A3M4C5H0
Locus tag C6H34_RS29435 Protein ID WP_005730485.1
Coordinates 21900..22085 (-) Length 62 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6H34_RS29430 21638..21910 - 273 WP_003348606.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C6H34_RS29435 21900..22085 - 186 WP_005730485.1 hypothetical protein Antitoxin
C6H34_RS29440 22136..22414 - 279 WP_003320513.1 hypothetical protein -
C6H34_RS29445 22507..23142 - 636 WP_065348598.1 recombinase family protein -
C6H34_RS29450 23389..24369 + 981 Protein_22 Y-family DNA polymerase -
C6H34_RS29455 24559..24789 + 231 WP_081591423.1 DUF4113 domain-containing protein -
C6H34_RS31025 24823..25092 - 270 WP_024421178.1 hypothetical protein -
C6H34_RS29465 25293..26297 - 1005 WP_005615818.1 ParB/RepB/Spo0J family partition protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..70589 70589


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10199.67 Da        Isoelectric Point: 5.0749

>T293901 WP_003348606.1 NZ_LT963399:c21910-21638 [Pseudomonas cerasi]
VLVEWLPQALEALEEIAGYLAERNPYAAEQMQATLEATVEALPLHPYIHRPGRVPGTREAVVHPNYLVVYRVGTERISIL
DVLHARQEYP

Download         Length: 273 bp

Antitoxin


Download         Length: 62 a.a.        Molecular weight: 7292.18 Da        Isoelectric Point: 7.2040

>AT293901 WP_005730485.1 NZ_LT963399:c22085-21900 [Pseudomonas cerasi]
MSIQLDPRVSEFETQEQADNYDRWFRQRIEHSLADPRPPVPHDEAMARVRAMIEAKRRRAS

Download         Length: 186 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3M4C5F0

Antitoxin

Source ID Structure
AlphaFold DB A0A3M4C5H0

References