293899

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PfiT-PfiA/ParE-Phd
Location 10052..10663 Replicon plasmid PP3
Accession NZ_LT963398
Organism Pseudomonas cerasi isolate PL963

Toxin (Protein)


Gene name PfiT Uniprot ID A0A193SFX2
Locus tag C6H34_RS28890 Protein ID WP_065348564.1
Coordinates 10313..10663 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name PfiA Uniprot ID Q6VE98
Locus tag C6H34_RS28885 Protein ID WP_011152898.1
Coordinates 10052..10300 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6H34_RS28865 5096..6670 - 1575 WP_065348574.1 diguanylate cyclase -
C6H34_RS28870 7109..7894 - 786 Protein_11 methyl-accepting chemotaxis protein -
C6H34_RS28875 8418..8732 + 315 WP_065348583.1 hypothetical protein -
C6H34_RS28880 8758..9720 - 963 WP_065348573.1 tyrosine-type recombinase/integrase -
C6H34_RS28885 10052..10300 + 249 WP_011152898.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
C6H34_RS28890 10313..10663 + 351 WP_065348564.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C6H34_RS28895 10770..11174 - 405 WP_065348582.1 DUF4279 domain-containing protein -
C6H34_RS30885 11372..11779 - 408 WP_065348563.1 hypothetical protein -
C6H34_RS28900 11776..14541 - 2766 WP_065348562.1 RHS repeat-associated core domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..81323 81323


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-91)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12947.79 Da        Isoelectric Point: 4.1953

>T293899 WP_065348564.1 NZ_LT963398:10313-10663 [Pseudomonas cerasi]
MNTFALRFTEVAQQSIEDQVEHLAITQGFSSAAQRIDTLIDAIQDKLLSTPLGYPVSPQLSELGVLHYRELNTDGYRIFY
EVMDSDGITDIAVLLVLGGKQSVEQALIRYCLLQPM

Download         Length: 351 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9329.71 Da        Isoelectric Point: 9.8452

>AT293899 WP_011152898.1 NZ_LT963398:10052-10300 [Pseudomonas cerasi]
MRVETISYLKRNAADLPLDEPLVVTQNGVPAYVVESYADRKRRDEAIALVKLLAISSREYAQGKHCSTDELKARLSRRFA
HK

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A193SFX2

Antitoxin

Source ID Structure
AlphaFold DB A0A7V8LY57

References