Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 4228758..4229293 Replicon chromosome
Accession NZ_LT962688
Organism Methylorubrum extorquens strain TK 0001

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag TK0001_RS19940 Protein ID WP_056507173.1
Coordinates 4228758..4229048 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag TK0001_RS19945 Protein ID WP_056507176.1
Coordinates 4229045..4229293 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
TK0001_RS19910 4224064..4224264 + 201 WP_003605412.1 hypothetical protein -
TK0001_RS19915 4224487..4225111 + 625 Protein_3938 TetR family transcriptional regulator -
TK0001_RS19920 4225131..4225475 - 345 WP_003605408.1 DUF1330 domain-containing protein -
TK0001_RS19925 4225478..4226177 - 700 Protein_3940 orotidine-5'-phosphate decarboxylase -
TK0001_RS19930 4226502..4228029 + 1528 Protein_3941 alginate export family protein -
TK0001_RS19935 4228037..4228676 - 640 Protein_3942 uracil-DNA glycosylase family protein -
TK0001_RS19940 4228758..4229048 - 291 WP_056507173.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
TK0001_RS19945 4229045..4229293 - 249 WP_056507176.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
TK0001_RS19950 4229427..4230929 + 1503 WP_101476146.1 glucose-6-phosphate dehydrogenase -
TK0001_RS19955 4231125..4232492 + 1368 WP_056507183.1 SWIM zinc finger family protein -
TK0001_RS19960 4232492..4234075 + 1584 WP_056507185.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-92)

Antitoxin

Antitoxin ParD

(1-79)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11025.59 Da        Isoelectric Point: 10.5105

>T293867 WP_056507173.1 NZ_LT962688:c4229048-4228758 [Methylorubrum extorquens]
MSVRLSPRARADLSRIWDDSAERWGADQADRYIRLLAGGFDRLAEDPARGLRADEIRKGYFRLSVGSHVLFYRLGAEGGI
EVIRILHGRMDFKRHL

Download         Length: 291 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9034.99 Da        Isoelectric Point: 4.5292

>AT293867 WP_056507176.1 NZ_LT962688:c4229293-4229045 [Methylorubrum extorquens]
MPRNTSVSLGEHFAQFIDRQVEGGRYGSASEVVRAGLRLLEEQEAALNTLRAALIEGEESGSPEPFDTETFLREKREGAI
RG

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References