Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 6008679..6009226 Replicon chromosome
Accession NZ_LT962481
Organism Pseudomonas syringae pv. syringae isolate CFBP2118

Toxin (Protein)


Gene name relE Uniprot ID A0A0L8IUR7
Locus tag C6H33_RS27255 Protein ID WP_003401398.1
Coordinates 6008679..6008954 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0L8IV93
Locus tag C6H33_RS27260 Protein ID WP_003401400.1
Coordinates 6008954..6009226 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6H33_RS27230 6003953..6004948 + 996 WP_011269432.1 NAD-dependent epimerase -
C6H33_RS27235 6004960..6005703 + 744 WP_024640371.1 glycosyltransferase family 2 protein -
C6H33_RS27240 6005700..6005984 + 285 WP_003367870.1 lipid-A-disaccharide synthase N-terminal domain-containing protein -
C6H33_RS27245 6005981..6007510 + 1530 WP_096126716.1 glycosyltransferase family 39 protein -
C6H33_RS27250 6007552..6008532 + 981 WP_104724337.1 SdiA-regulated domain-containing protein -
C6H33_RS27255 6008679..6008954 - 276 WP_003401398.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C6H33_RS27260 6008954..6009226 - 273 WP_003401400.1 ribbon-helix-helix domain-containing protein Antitoxin
C6H33_RS27265 6009426..6010151 + 726 WP_024640368.1 NAD(P)-dependent oxidoreductase -
C6H33_RS27270 6010258..6012093 - 1836 WP_104724339.1 glutamine--fructose-6-phosphate transaminase (isomerizing) -
C6H33_RS27275 6012103..6012870 - 768 WP_010422861.1 DeoR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-47)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10774.29 Da        Isoelectric Point: 9.5559

>T293862 WP_003401398.1 NZ_LT962481:c6008954-6008679 [Pseudomonas syringae pv. syringae]
MELKWTSKALSDIARLYEFLAAVNQPAAARTVQQLTSAPTTLRTNPRIGERLEEFEPRDVRRIQIGHYEMRYEIVNSTVY
LLRLWHSREDR

Download         Length: 276 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10107.41 Da        Isoelectric Point: 5.6994

>AT293862 WP_003401400.1 NZ_LT962481:c6009226-6008954 [Pseudomonas syringae pv. syringae]
MATTAKTRSVTAHVPEQLAQKVDLMAERLERSKNWIVKQALSAWIDQEEERSRLTREALADVDAGRIIDHQAVQAWADSL
STDTALPLPR

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0L8IUR7

Antitoxin

Source ID Structure
AlphaFold DB A0A0L8IV93

References