Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 1549775..1550300 Replicon chromosome
Accession NZ_LT962481
Organism Pseudomonas syringae pv. syringae isolate CFBP2118

Toxin (Protein)


Gene name stbE Uniprot ID Q4ZPQ9
Locus tag C6H33_RS07440 Protein ID WP_011268681.1
Coordinates 1549775..1550065 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q4ZPR0
Locus tag C6H33_RS07445 Protein ID WP_003402372.1
Coordinates 1550055..1550300 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C6H33_RS07415 1544883..1545353 - 471 WP_104723213.1 MaoC family dehydratase -
C6H33_RS07425 1545722..1547410 + 1689 WP_058398949.1 long-chain-fatty-acid--CoA ligase FadD2 -
C6H33_RS07435 1547766..1549457 + 1692 WP_011268682.1 long-chain-fatty-acid--CoA ligase FadD1 -
C6H33_RS07440 1549775..1550065 - 291 WP_011268681.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C6H33_RS07445 1550055..1550300 - 246 WP_003402372.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
C6H33_RS07450 1550474..1554385 + 3912 WP_104724379.1 ATP-dependent RNA helicase HrpA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-81)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-71)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11010.01 Da        Isoelectric Point: 10.7294

>T293861 WP_011268681.1 NZ_LT962481:c1550065-1549775 [Pseudomonas syringae pv. syringae]
MTFKLEFLPSALKEWEKLGHTIRVQLKKKLLERLGLPRIPGDALHGMPDHYKIKLRSAGYRLVYRVEEDRVVVTVVAVGK
RERGNIYDSAKGRLGP

Download         Length: 291 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8827.22 Da        Isoelectric Point: 4.5349

>AT293861 WP_003402372.1 NZ_LT962481:c1550300-1550055 [Pseudomonas syringae pv. syringae]
MQSILADVAVSVSELKKNPSAVLSGAHGLPVAVLNHNKVMGYMVPAEVFEAMMERLDDLDLAELIKSRQHEKPVSVDIDD
L

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q4ZPQ9

Antitoxin

Source ID Structure
AlphaFold DB A0A3M2V2W1

References